Trauma

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Trauma

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Blood Products | Drug Therapy | Imaging

Blood Product & Fluid Transfusion

Multi red cell transfusion

Image: Shutterstock | Matej Kastelic

Red Cells, Platelets & Plasma

Holcomb. Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma: The PROPPR Randomized Clinical Trial. JAMA 2015;313(5):471

Red Cells & Plasma

Crombie. Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised, controlled, phase 3 trial. Lancet Haematology 2022;epublished March 7th

Plasma

Saline

Bickell. Immediate versus delayed fluid resuscitaion for hypotensive patients with penetrating torso injuries. N Engl J Med 1994;331:1105-1109

Drug Therapy

Insulin infusion in the ICU

Image: Shutterstock | Komsan Loonprom

Corticosteroids

Roquilly. Hydrocortisone therapy for patients with multiple trauma. The randomized controlled HYPOLYTE study. JAMA 2011;305(12):1201-1209

Antifibrinolytics

CRASH-2 trial collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010;376:23-32

Imaging

$Bilateral femoral fractures$

Image: Shutterstock | Yok_onepiece

Red Cells, Platelets & Plasma

Holcomb. Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma: The PROPPR Randomized Clinical Trial. JAMA 2015;313(5):471

Pan Scan

Sierink. Immediate total-body CT scanning versus conventional imaging and selective CT scanning in patients with severe trauma (REACT-2): a randomised controlled trial. Lancet 2016;epublished June 28th

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