Welcome to the 764th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. 

The highlights of this week's edition are randomised controlled trials on dapagliflozin and acute kidney injury following cardiac surgery & prone positioning in infants with acute bronchiolitis; systematic reviews and meta analyses on anabolic androgen therapy in critically ill adults & albumin for people with liver cirrhosis and bacterial infections; and observational studies on rocuronium dose and first-attempt intubation success in the critically ill & video versus direct laryngoscopy for tracheal intubation in trauma. 

There are also guidelines on acute-on-chronic liver failure & candidemia and invasive candidiasis; narrative reviews on antiseizure medication dosing and monitoring in the intensive care unit & mechanical ventilation – physiology, mechanism and modes; editorials on oxygen exposure in patients with brain injury: beyond static thresholds & questions that remain for Impella use in ST-elevation myocardial infarction; and commentaries on interpreting protein dose trials in critical illness & optimizing endpoints in early phase clinical trials of acute respiratory distress syndrome. 

If you only have time to read one review article this week, try this one on twenty-five years of septic shock hemodynamic resuscitation trials: a conceptual perspective. 

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