Welcome to the 581st Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials on extracorporeal CPR for refractory out-of-hospital cardiac arrest & higher protein dosing in critically ill patients with high nutritional risk; systematic reviews and meta analyses on dexmedetomidine for the prevention of delirium & extracorporeal cardiopulmonary resuscitation; and observational studies on a wearable cardiac ultrasound imager & diastolic blood pressure thresholds during pediatric cardiopulmonary resuscitation. There are also guidelines on pediatric Acute Respiratory Distress Syndrome & surgical management and mechanical circulatory support in high-risk pulmonary embolisms; narrative reviews on liberation from mechanical ventilation in the cardiac ICU & biventricular assist devices and the total artificial heart; editorials on liberation from continuous kidney replacement therapy & advancing precision-based antimicrobial dosing; and commentaries on whether nephrologists or intensivists should manage kidney replacement therapy in the ICU & conditional power: how likely is trial success?
If you only have time to read one review article this week, try this one on ultrasonographic assessment of diaphragmatic function and its clinical application in the management of patients with acute respiratory failure.
We've been quietly working on the CCR23 programme over the past several months and hope to start announcing the provisional trials and faculty this week. As usual, we'll host major trial results, review some of the best trials of the previous 12 months and have expert panel discussions on various aspects of clinical trials. If you haven't yet registered, don't wait too long, or you might be disappointed. Belfast gets very busy during the Summer, so book your hotel now before the rush. We have discounted rates with partner hotels available on the meeting webpage.
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ps: many thanks to my friends and colleagues in Denmark for such superb hospitality this week at the wonderful Danish Intensive Care Symposium.
I hope you find this newsletter useful.
Until next week