Critical Care Reviews Newsletter

Welcome to the 578th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials comparing remifentanil with neuromuscular blockers during rapid sequence intubation & norepinephrine plus dobutamine with epinephrine in children with fluid refractory cold septic shock; systematic reviews and meta analyses on muscle wasting during critical illness & epinephrine administration interval during adult cardiac arrest; and observational studies on the effect of blood pressure on mortality following out-of-hospital cardiac arrest & the association of appropriate empirical antimicrobial therapy with in-hospital mortality in patients with bloodstream infections.

There are also guidelines on thrombectomy procedures in stroke patients & pediatric traumatic hemorrhagic shock; narrative reviews on post-cardiac arrest syndrome & hemorrhagic shock; editorials on clinical practice guideline methodology & perioperative dialysis; and commentaries on acute kidney injury & the dangers of non-randomized, observational studies.

If you only have time to read one review article this week, try this one on new antibiotics for Gram-negative pneumonia.

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