Critical Care Reviews Newsletter

Newsletter 559  |  August 29th, 2022

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Welcome to the 559th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlight of this week's edition is the publication of the factorial BOX trial, comparing blood-pressure targets and oxygen targets in comatose survivors of out-of-hospital cardiac arrest. Other notable papers include a randomised controlled trial investigating acetazolamide in acute decompensated heart failure with volume overload; systematic reviews and meta analyses on COVID-19 postacute care major organ damage & prophylactic platelet transfusions; and observational studies on antiseizure medication in patients with aneurysmal subarachnoid haemorrhage & terlipressin use and respiratory failure in patients with hepatorenal syndrome type 1 and severe acute-on-chronic liver failure.

There are also new ESC/ERS guidelines on pulmonary hypertension & the cardiovascular assessment and management of patients undergoing non-cardiac surgery; narrative reviews on autoimmune encephalitis & venting during venoarterial extracorporeal membrane oxygenation; an editorial on extubation failure in patients with acute brain injury; and commentaries on new drugs for acute kidney injury & vitamin C in sepsis.

If you only have time to read one review article this week, try this one on acid-base disorders in the critically iII patient.

The latest visual abstract from Jakub Fronczek is on the TTM2 trial. Niklas Nielsen's presentation of this trial from CCR22 is due for release this week.

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I hope you find this newsletter useful.

Until next week




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