Critical Care Reviews Newsletter

Welcome to the 557th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the week August 8th to 14th.

The highlights of this week's edition are randomised controlled trials on levetiracetam for the prevention of epileptic seizures in the acute phase of intracerebral haemorrhage & high-flow versus venturi mask oxygen therapy to prevent re-intubation in hypoxemic patients after extubation; systematic reviews and meta analyses on targeted temperature management after in-hospital cardiac arrest & the association of dual antiplatelet therapy with ticagrelor with vein graft failure after coronary artery bypass graft surgery; and observational studies on ecological effects of selective oral decontamination on multidrug‑resistance bacteria acquired in the ICU & peri-intubation cardiovascular collapse in patients who are critically ill.

There are also guidelines on hepatic encephalopathy & antithrombotic therapy; narrative reviews on optimal perfusion targets in cardiogenic shock & plasma exchange in the ICU; an editorial on future perspectives in the diagnosis and treatment of sepsis and septic shock; and commentaries on central venous pressure & protective ventilation; as well as correspondence on frailty in the ICU & high-flow oxygen therapy for severe hypoxemia. 

If you only have time to read one review article this week, try this one on how assessing hemodynamics can help to assess volume status.

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