Welcome to the 527th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. It's a small newsletter this week, the highlights of which are two series, one from Anaesthesia on brain injuries and the other from the BJA on mass casualty medicine.
Join us on Tuesday January 18th 20:00 (UTC +0) for the livestream of the PLUS trial results presentation. PLUS is a large multi-centre randomised controlled trial comparing 0.9% saline with plasmalyte-148 in 5000 critically ill patients. It follows on from the BASICS trial result we had in August and further adds to the growing evidence base in the field. After Simon Finfer presents the results of the PLUS trial, Naomi Hammond will present an up-to-date systematic review and meta analysis comparing balanced fluids with 0.9% saline. We have a superb faculty organised, with Deborah Cook giving the editorial, and a panel discussion including John Kellum, Gordon Guyatt, Tomoko Fujii and Jeff Drazen. The livestream will be freely available on the Critical Care Reviews website.