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Critical Care Reviews Newsletter

Newsletter 523  |  December 19th 2021

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Merry Christmas

Welcome to the 523rd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are the RADAR2 randomised controlled trial, investigating the feasibility of conservative fluid administration and deresuscitation in critical illness, as well as an RCT comparing etomidate with ketamine for emergency endotracheal intubation; systematic reviews and meta analyses on utilization and outcomes of extracorporeal CO2 removal & medical futility regarding cardiopulmonary resuscitation in in-hospital cardiac arrests; and observational studies on capillary leak in critically ill patients & albumin and fibrinogen kinetics in sepsis.

There are also guidelines on the use of lung ultrasound in critically ill patients with coronavirus disease 2019 & early management of patients with aneurysmal subarachnoid hemorrhage in a hospital without neurosurgical/neuroendovascular facilities; narrative reviews on nutrition support for critically ill patients & extracorporeal haemoadsorption; editorials on Omicron SARS-CoV-2 variant: what we know and what we don’t & extracorporeal membrane oxygenation for COVID-19; and commentaries on applying syndemic theory to acute illness & the evolving role of ECMO in COVID-19.

If you only have time to read one review article this week, try this one on the current practice and evolving concepts in septic shock resuscitation.


Randomised Controlled Trials

Systematic Review & Meta Analyses

Observational Studies





I hope you find this newsletter useful.

Merry Christmas



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