Welcome to the 517th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials on extubation techniques in critically ill adults & efficacy and safety of enteral erythromycin estolate in combination with intravenous metoclopramide vs intravenous metoclopramide monotherapy in mechanically ventilated patients with enteral feeding intolerance; systematic reviews and meta analyses on non-invasive ventilation versus invasive weaning in critically ill adults & ECPR for out-of-hospital cardiac arrest; and observational studies on death due to irreversible hypoxemic respiratory failure in ARDSnet clinical trials & association of oliguria with acute kidney injury diagnosis, severity assessment, and mortality among patients with critical illness.
There are also guidelines on environmentally-sustainable anaesthesia & reciprocal organ interactions during heart failure; narrative reviews on ultrasound in neurocritical care & hyperoxia pathophysiology in the perioperative setting; editorials on perioperative eye protection & reshaping obstetric critical care with point-of-care ultrasound; and commentaries on cardiac injury in COVID‑19 & understanding significance testing.
If you only have time to read one review article this week, try this one on dynamic extracorporeal life support.
New Partnership with My Intensive Care
We're excited to announce a new partnership with My Intensive Care, a breakthrough digital platform for managing all aspects of your ICU. Critical Care Reviews has expanded significantly over the past 12 months, putting pressure on every aspect of our project. This new agreement allows us to continue to grow and freely provide the latest updates in critical care to all our users.
Our next livestream is on Tuesday, November 30th, at 19:30 UTC+0 and features the COCA trial results presentation from Lars Andersen and colleagues. COCA investigates calcium for out-of-hospital cardiac arrest. Gavin Perkins, chief investigator for the PARAMEDIC2 trial, investigating adrenaline for out-of-hospital cardiac arrest, will deliver the independent editorial. As usual, the livestream will be free to watch, although there will be a small charge for those wishing to claim CPD/CME points (registration required - not yet open).
There have been many inquires asking when registration will open for CCR22, on next June 15th to 17th in Titanic Belfast. Our aim is to open in 3-4 weeks, starting with an initial batch of tickets for registered CCR users.