Latest REMAP-CAP podcast series episode on ivermectin with Prof Alistair Nichol
Welcome to the 509th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials on convalescent plasma for hospitalized patients with COVID-19 & cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis; systematic reviews and meta analyses on the effect of vitamin C on mortality in patients with sepsis & timing of tracheostomy in acute traumatic spinal cord injury; and observational studies on oxygenation targets in ICU patients with COVID-19 & the association of hyperoxaemia and hypoxaemia with harm in patients with ARDS.
There are also guidelines on the management of septic shock and sepsis-associated organ dysfunction in children & mass critical care surge response during COVID-19; narrative reviews on oxygen therapy for critically ill and post-operative patients & what intensive care registries can teach us about outcomes; commentaries on whether it's time to abandon ARDS & the management of multi-morbidity in elderly patients; as well as correspondence on the effect of vaccination on transmission of SARS-CoV-2 & opioids for sedation. If you only have time to read one review article this week, try this one on extracorporeal cardiopulmonary resuscitation in adults.