Welcome to the 508th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlight of this week's edition is the publication of the REST trial, presented at eCCR21 in January. Other notable publications include randomised controlled trials comparing low-normal vs high-normal oxygenation targets & an investigation on the efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19; systematic reviews and meta analyses on targeted temperature management in adult cardiac arrest & ivermectin for preventing and treating COVID‐19; and observational studies on one-year outcomes of critically ill paediatric patients post–COVID-19 multisystem inflammatory syndrome & pulmonary aspergillosis in critically ill COVID-19 patients.
There are also guidelines on valvular heart disease & anticoagulation for thromboprophylaxis in patients with COVID-19; narrative reviews on pediatric airway management in times of COVID-19 & kidney failure after liver transplantation; editorials on climate change & early mobilization and rehabilitation; and commentaries on mechanical support strategies for children with severe cardiac failure & selective digestive decontamination; as well as correspondence on the resurgence of SARS-CoV-2 infection in a highly vaccinated health system workforce & COVID-19 associated pulmonary aspergillosis.
If you only have time to read one review article this week, try this one, from the annual Annual Update in Intensive Care and Emergency Medicine 2021 book, on whether there is still a place for aortic counterpulsation in cardiac surgery and patients with cardiogenic shock.