Critical Care Reviews Newsletter

Welcome to the 506th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are a randomised controlled trial on awake prone positioning for COVID-19 acute hypoxaemic respiratory failure; systematic reviews and meta analyses on pulmonary artery catheterization in patients with cardiogenic shock & the efficacy of vitamin C, thiamine, and corticosteroid therapy in adult sepsis patients; and observational studies on early convalescent plasma for high-risk outpatients with Covid-19 & lung recruiting effect of prone positioning in spontaneously breathing patients with COVID-19 assessed by electrical impedance tomography.

There are also guidelines on ventilatory support at home for children & adsorptive hemofiltration for sepsis management; narrative reviews on delirium in critical illness & optimal timing to perform surgical stabilization of rib fractures; editorials on oxygenation indices in noninvasive ventilation & hepatorenal syndrome management; and commentaries on confronting the Delta variant of SARS-CoV-2 & preventing a pandemic's toll—we've been here before; as well as correspondence on driving pressure in COVID-19 ARDS & interleukin-6 receptor antagonists in critically ill patients with Covid-19.

If you only have time to read one review article this week, try this one on the ethics of ECPR research.