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Critical Care Reviews Newsletter

Newsletter 495  |  June 7th 2021

TTM2 Trial Results Livestream June 16th

Welcome to the 495th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. I'm out of time this week, so I'll leave you to browse the articles below. If you are in the UK, a quick reminder that the UK Critical Care Research Forum is on virtually this Thursday and Friday.


Critical Care Reviews Trials Results Meeting - The TTM2 Trial

Critical Care Reviews is delighted to announce the hosting of the much anticipated results of the TTM2 trial, on Wednesday night, June 16th, 20:15 to 22:00 UTC. As a follow up to the landmark TTM trial, comparing targeted temperature management of 33°C with 36°C in unconscious survivors of an out-of-hospital cardiac arrest, TTM2 compares a target temperature of 33°C after cardiac arrest with normothermia and early treatment of fever (≥37.8°C). The trial background and results will be delivered by three members of the TTM2 trial team (Niklas Nielsen, Josef Dankiewicz & Gisela Lilja); the editorial will be given by Prof Stephen Bernard, the chief investigator of the original Australian hypothermia trial from 2002; and the panel discussion will include Prof Jerry Nolan (Editor-in-Chief Resuscitation journal and European Resuscitation Council member; Bath, England), Prof Kathy Rowan (Director of ICNARC, London, England), and Prof Catherine Hough (Intensivist & Researcher, Oregon, USA). As usual, this will be a free livestream on the CCR wesite, accessible to all without the need for registration. Please do share this information with your colleagues to maximise the dissemination of the results of this important trial.


Randomised Controlled Trials

Systematic Review & Meta Analyses

Observational Studies





Case Reports

I hope you find this newsletter useful.

Until next week




Supported by the Health Research Board