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Critical Care Reviews Newsletter

Newsletter 485  |  March 30th 2021


Welcome to the 485th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature from last week, March 22nd to 28th.

The highlights of this edition are a randomised controlled trial comparing helmet noninvasive ventilation with high-flow nasal oxygen in patients with COVID-19, and two large international observational studies, on intubation practices and adverse peri-intubation events in critically ill patients & ventilator weaning and discontinuation practices. The European Resuscitation Council also released their 2021 guidelines on cardiac arrest, as well as a joint ESICM guideline on post-resuscitation care.

There are also narrative reviews on haemodynamic instability during acute kidney injury and acute renal replacement therapy & COVID-19-associated organ dysfunction in the ICU: opportunities for translational research; as well as commentaries on the Coronavirus pandemic 1 year on—what went wrong & how COVID-19 affects the brain.

If you only have time to read one review article this week, try this one on haemodynamically-guided therapy for cardiogenic shock.

Critical Care Reviews Podcast

Last week, I was fortunate to have the opportunity to chat with Vincenzo Russotto and Sheila Myatra about the INTUBE study. It's a fascinating description of intubation practices in the critically ill worldwide as well as a documentation of peri-intubation adverse events.


I hope you find this newsletter useful.

Until next week




Supported by the Health Research Board