Welcome to the 484th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are a randomised controlled trial comparing intermediate-dose with standard-dose prophylactic anticoagulation in critically ill patients with COVID-19; systematic reviews and meta analyses on corticosteroids in cardiac arrest & neuromuscular blocking agents in ARDS; and observational studies on the four-month clinical status of a cohort of patients after hospitalization for COVID-19 & the assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020.
There are also guidelines on the diagnosis of invasive fungal infections and an expert consensus statement on the management of COVID-19-related acute respiratory failure; narrative reviews on COVID-19, immunothrombosis and venous thromboembolism & cardiac function after cardiac arrest; editorials on ethics criteria for scarce resource allocation in the era of COVID-19 & novel renal biomarkers of acute kidney injury; and commentaries on long-term outcomes after critical illness & Kaplan-Meier curves, log-rank tests, and Cox regression for time-to-event data.
If you only have time to read one review article this week, try this one on fifty years of mechanical ventilation—1970s to 2020.
I hope you find this newsletter useful.
Until next week
Supported by the Health Research Board