Critical Care Reviews Newsletter

Newsletter 481  |  February 28th 2021

Dr Lennie Derde (Utrecht, The Netherlands) presents the results of the REMAP-CAP IL-6 Receptor Antagonist Domain

Welcome to the 481st Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlight of this week's edition is the presentation and publication of the REMAP-CAP IL-6 receptor antagonist domain results, which we hosted on Thursday night. The full recording is available on the CCR homepage and the paper was simultaneously published in the New England Journal of Medicine.

In other news, the BACLOREA trial, investigating the effect of high-dose baclofen on agitation-related events among patients with unhealthy alcohol use receiving mechanical ventilation, presented at eCCR21, has been published in JAMA; the VICTAS trial, the latest RCT examining the effect of vitamin C, thiamine, and hydrocortisone in patients with sepsis is also out in JAMA;  and the final report of the dexamethasone arm of the RECOVERY randomised controlled trial has been published too.


I hope you find this newsletter useful.

Until next week




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