Paper of the Day

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2023

Other Years: 2024 | 2023 | 2022

Wednesday, April 30th

2025

Carter. The management of acute meningitis: an update. Clin Med 2022;22(5):396-400

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Months

January | February | March | April

April

30th	Sepsis	Carter. The management of acute meningitis: an update. Clin Med 2022;22(5):396-400
29th	Neuro	Ranjan. Pathophysiology, diagnosis and management of cerebral venous thrombosis: A comprehensive review. Medicine 2023;102(48):e36366
28th	Circulatory	McGuire. Management Strategies for Acute Pulmonary Embolism in the ICU. Chest 2024;166(6):1532-1545
27th	Resuscitation	Jaeger. A Narrative Review of Drug Therapy in Adult and Pediatric Cardiac Arrest. Rev Cardiovasc Med 2023;24(6):163
26th	Nutrition	Blaser. How to avoid harm with feeding critically ill patients: a synthesis of viewpoints of a basic scientist, dietitian and intensivist. Crit Care 2023;27(1):258
25th	Respiratory	Liu. Recent advances in the development of invasive ventilator liberation. Trends Anaesth Crit Care 2025;60:101521
24th	Renal	Al Sahlawi. Peritoneal Dialysis in Critically Ill Patients Time for a Critical Reevaluation? Clin J Am Soc Nephrol 2023;18(4):512-520
23rd	Respiratory	Abrams. Risks and Benefits of Ultra–Lung-Protective Invasive Mechanical Ventilation Strategies with a Focus on Extracorporeal Support. Am J Respir Crit Care Med 2022;205(8):873–882
22nd	Immunology	Nie. Deep insight into cytokine storm: from pathogenesis to treatment. Sig Transduct Target Ther 2025;10:112
21st	Neuro	Latronico. Critical Illness Weakness, Polyneuropathy and Myopathy: Diagnosis, treatment, and long-term outcomes. Crit Care 2023;27:439
20th	Skin	Calle. DRESS syndrome: A literature review and treatment algorithm. World Allergy Organ J 2023;16(3):10067
19th	Liver	Diaz-Soto. Management of varices and variceal hemorrhage in liver cirrhosis: a recent update. Therap Adv Gastroenterol 2022:15:17562848221101712
18th	Oncology	Thandra. Oncologic Emergencies-The Old, the New, and the Deadly. J Intensive Care Med 2020;35(1):3-13
17th	Respiratory	Póvoa. Biomarkers in pulmonary infections: a clinical approach. Ann Intensive Care 2024;14:113
16th	Toxicology	Kast. Management of alcohol withdrawal syndromes in general hospital settings. BMJ 2025;388:e080461
15th	Airway	Hickey. Approach to the Physiologically Challenging Endotracheal Intubation in the Intensive Care Unit. Respir Care 2023;68(10):1438–1448
14th	Circulatory	Apte. Pharmacotherapy in Ventricular Arrhythmias. Cardiology 2023;148 (2):119–130
13th	Neuro	Rodríguez-Blanco. Neuromuscular blocking agents in the intensive care unit. J Internat Med Res 2022;50(9)
12th	Sepsis	Damiani. Microcirculation-guided resuscitation in sepsis: the next frontier? Front Med 2023;10:1212321
11th	Nutrition	de Man. Nutrition in the intensive care unit: from the acute phase to beyond. Intensive Care Med 2024;50(7):1035-1048
10th	Trauma	Meza Monge. Navigating hemorrhagic shock: biomarkers, therapies, and challenges in clinical care. Biomedicines 2024;12:2864
9th	Sepsis	Minter. Contemporary Management of Staphylococcus aureus Bacteremia—Controversies in Clinical Practice. Clinical Infectious Diseases 2023;77(11):e57–e68
8th	Renal	Melchers. Management of hypocalcaemia in the critically ill. Curr Opin Crit Care 2023;29(4):330-338
7th	Respiratory	Kim. Management of tracheo-oesophageal fistula in adults. Eur Respir Rev 2020;29(158):200094
6th	Haematological	Cox. Basics of diagnosis and treatment of venous thromboembolism. J Thromb Haemost 2025;23(4):1185-1202
5th	Neuro	Wijdicks. Identifying encephalopathies from acute metabolic derangements. J Intern Med 2022;292(6):846-857
4th	Liver	Ballester. Extracorporeal liver support and liver transplantation for acute-on-chronic liver failure. Liver Int 2025;45(3):e15647
3rd	Haematological	Knight. Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management. BMJ 2023;380:e069717
2nd	Resuscitation	Geller. Sedation and shivering management after cardiac arrest. Eur Heart J Acute Cardiovasc Care 2023;12(8):518-524
1st	Circulatory	Kochar. Catheter-directed interventions for pulmonary embolism. Eur Heart J Acute Cardiovasc Care 2022;11(9):721–727

March

31st	Renal	De Vlieger. Kidney Dysfunction After Traumatic Brain Injury: Pathophysiology and General Management. Neurocrit Care 2022:38:504-516
30th	Respiratory	Redaelli. Nitric oxide: Clinical applications in critically ill patients. Nitric Oxide 2022;121:20–33
29th	Sepsis	Jones. Assessment and management of necrotizing fasciitis. Br J Surg 2024;111(9):znae204
28th	Neuro	Ranjan. Pathophysiology, diagnosis and management of cerebral venous thrombosis: A comprehensive review. Medicine 2023;102(48):e36366
27th	Metabolic	Müller. Lactate: The Fallacy of Oversimplification. Biomedicines 2023;11:3192
26th	Circulatory	Spagnolo. Periprocedural myocardial infarction and injury. Eur Heart J Acute Cardiovasc Care 2024;13(5):433-445
25th	Airway	Wiles. Airway management in patients with suspected or confirmed traumatic spinal cord injury: a narrative review of current evidence. Anaesthesia 2022;77(10):1120-1128
24th	Liver	Durand. Fluid resuscitation in patients with cirrhosis and sepsis: A multidisciplinary perspective. J Hepatol 2023;79(1):240-246
23rd	Toxicology	Seifert. Snake Envenomation. N Engl J Med 2022;386(1):68-78
22nd	Trauma	Lee. Cardiac Trauma: A Review of Penetrating and Blunt Cardiac Injuries. Am Surg 2024;91(3):423-433
21st	Neuro	Bellanti. Guillain-Barré syndrome: a comprehensive review. Eur J Neurol 2024;31(8):e16365
20th	Respiratory	Wick. Acute respiratory distress syndrome. BMJ 2024;387:e076612
19th	Haematological	Satoh. Practical approach to thrombocytopenia in patients with sepsis: a narrative review. Thromb J 2024;22(1):67
18th	Metabolic	Do. Metabolic Alkalosis Pathogenesis, Diagnosis, and Treatment: Core Curriculum 2022. Am J Kidney Dis 2022;80(4):536-551
17th	Nutrition	Gunst. Toward nutrition improving outcome of critically ill patients: how to interpret recent feeding RCTs? Crit Care 2023;27(1):43
16th	Respiratory	Arnott. Nebuliser therapy in critical care: The past, present and future. J Intensive Care Soc 2023;2023;25(1):78-88
15th	Circulatory	Hansen. Use of Inotropic Agents in Advanced Heart Failure: Pros and Cons. Cardiology 2024;149(5):423–437
14th	GI	Buscail. Postoperative ileus: A pharmacological perspective. Br J Pharmacol 2022;179(13):3283-3305
13th	Neuro	McCredie. How do we identify the crashing traumatic brain injury patient - the intensivist's view. Curr Opin Crit Care 2021;27(3):320-327
12th	Endocrine	Wright. Management of diabetic ketoacidosis in children. BJA Educ 2023;23(9):364-370
11th	Toxicology	Mikkelsen. Serotonin syndrome-A focused review. Basic Clin Pharmacol Toxicol 2023;133(2):124-129
10th	Liver	Fernández. Acute liver failure: A practical update. JHEP Rep 2024;6(9):101131
9th	Trauma	Cioffi. Blunt abdominal trauma: watch and wait. Curr Opin Crit Care 2023;29(6):674-681
8th	Airway	Sakles. Preventing unrecognized esophageal intubation in the emergency department. JACEP Open 2023;4:e12951
7th	Circulatory	Van Regenmortel. Fluid-induced harm in the hospital: look beyond volume and start considering sodium. From physiology towards recommendations for daily practice in hospitalized adults. Ann Intensive Care 2021;11(1):79
6th	Renal	Escudero. New Insights Into Diuretic Use to Treat Congestion in the ICU: Beyond Furosemide. Front Nephrol 2022;2:879766
5th	Resuscitation	Kjaergaard. Haemodynamic, oxygenation, and ventilation targets after cardiac arrest: the current ABC of post-cardiac arrest intensive care. Eur Heart J Acute Cardiovasc Care 2023;12:513–517
4th	Nutrition	Ramaswamy. Nine Myths about Enteral Feeding in Critically Ill Adults: An Expert Perspective. Advances in Nutrition 2024;16(1):100345
3rd	Respiratory	Le Stang. Critical illness-associated limb and diaphragmatic weakness. Curr Opin Crit Care 2024;30(2):121-130
2nd	Sepsis	Doman. Temperature control in sepsis. Front Med 2023;10:1292468
1st	Neuro	Trujillo-gómez. Acute infections of the central nervous system in children and adults: diagnosis and management. Minerva Medica 2024;115(4):476-502

February

28th	GI	Hamesch. Practical management of severe acute pancreatitis. Eur J Intern Med 2024;epublished November 29th
27th	Circulatory	Kaemmerer. Pericardial tamponade, a diagnostic chameleon: from the historical perspectives to contemporary management. J Cardiothorac Surg 2023;18(1):60
26th	Neuro	Scheitz. Stroke-Heart Syndrome: Recent Advances and Challenges. J Am Heart Assoc 2022;11(17):e026528
25th	Resuscitation	Yao. Extracerebral multiple organ dysfunction and interactions with brain injury after cardiac arrest. Resusc Plus 2024;19:100719
24th	Haematological	Cardenas. Injury-induced endotheliopathy: What you need to know. J Trauma Acute Care Surg 2023;95(4):454-463
23rd	Renal	Birkelo. The Road to Precision Medicine for Acute Kidney Injury. Crit Care Med 2024;52(7):1127-1137
22nd	Airway	Wallace. Laryngeal complications after tracheal intubation and tracheostomy. BJA Educ 2021;21(7):250-257
21st	Liver	Heybe. Role of albumin infusion in cirrhosis-associated complications. Clin Exp Med 2024;24:58
20th	Sepsis	Nierhaus. Best-practice IgM- and IgA-enriched immunoglobulin use in patients with sepsis. Ann Intensive Care 2020;10(1):132
19th	Renal	Martens. Emerging Individualized Approaches in the Management of Acute Cardiorenal Syndrome With Renal Assist Devices. JACC: Heart Failure 2023;11(10):1289-1303
18th	Neuro	Boncyk. Management of pain and sedation in the intensive care unit. BMJ 2024;387:e079789
17th	Respiratory	Teo. Pneumomediastinum and pneumothorax in acute respiratory distress syndrome (ARDS) patients: a narrative review. Mediastinum 2023;8:3
16th	Toxicology	Motohashi. Toxicology in the emergency department: what's new? Br J Hosp Med 2022;83(9):1-16
15th	Neuro	Robba. Mastering the brain in critical conditions: an update. ICMx 2023;12:1
14th	Sepsis	Monnet. How I personalize fluid therapy in septic shock? Crit Care 2023;27(1):123
13th	Circulatory	Reynolds. Myocardial Infarction with Nonobstructive Coronary Arteries. Ann Rev Med 2023;74(1):171-188
12th	Liver	García-Martínez. Management of Hepatic Encephalopathy Associated with Advanced Liver Disease. Clin Drug Investig 2022;42(Suppl 1):5–13
11th	Respiratory	Abdulelah. Infective Pleural Effusions-A Comprehensive Narrative Review Article. Clin Pract 2024;14(3):870-881
10th	Metabolic	Pohanka. D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection. Biomed Res Int 2020;2020:3419034
9th	Trauma	Iida. State-of-the-art methods for the treatment of severe hemorrhagic trauma: selective aortic arch perfusion and emergency preservation and resuscitation-what is next? Acute Med Surg 2021;8(1):e641
8th	Renal	Zhang. Focus on oliguria during renal replacement therapy. J Anesth 2024;38:681–691
7th	Airway	Seltz Kristensen. Managing and securing the bleeding upper airway: a narrative review. Can J Anaesth 2020;67(1):128-140
6th	Sepsis & ID	Akafity. Diagnosis and management of malaria in the intensive care unit. J Intensive Med 2023;4(1):3-15
5th	Neuro	Barik . Use of Hypertonic Saline in Neuroanesthesia and Neurocritical Care Practice: A Narrative Review. J Neuroanaesth Crit Care 2023;10(01):012-020
4th	Circulatory	Münzel. Challenges posed by climate hazards to cardiovascular health and cardiac intensive care: implications for mitigation and adaptation. Eur Heart J Acute Cardiovasc Care 2024;13(10):731–744
3rd	Gastrointestinal	Roberts. The open abdomen in trauma, acute care, and vascular and endovascular surgery: comprehensive, expert, narrative review. BJS Open 2023;7(5):zrad084
2nd	Miscellaneous	Parekh. Ophthalmology in Critical Care. Ann Am Thorac Soc 2019;16(8):957–966
1st	Neuro	Ferrell. Extracorporeal Cardiopulmonary Resuscitation—Where Do We Currently Stand? Biomedicines 2025;13(1):204

January

31st	Sepsis	Chiscano-Camón. Current perspectives in the management of sepsis and septic shock. Front Med 2024;11:1431791
30th	Resuscitation	Paul. Point-of-care Ultrasound in Cardiac Arrest. Anesthesiology 2021;135(3):508-519
29th	Trauma	Kyle. Penetrating abdominal trauma. Br J Surg 2024;111(8):znae206
28th	Trauma	Sarani. Contemporary management of patients with multiple rib fractures: What you need to know. J Trauma Acute Care Surg 2024;97(3):337-342
27th	Circulatory	Bloom. State of Shock: Contemporary Vasopressor and Inotrope Use in Cardiogenic Shock. J Am Heart Assoc 2023;J Am Heart Assoc 2023;12(15):e029787
26th	Haematology	Patriarcheas. Antiphospholipid Syndrome: A Comprehensive Clinical Review. J Clin Med 2025;14:733
25th	Neuro	Rossetti. Status epilepticus in the ICU. Intensive Care Med 2023;50:1-16
24th	Renal	Acute kidney injury in patients with cirrhosis: Acute Disease Quality Initiative (ADQI) and International Club of Ascites (ICA) joint multidisciplinary consensus meeting. J Hepatol 2024;81(1):163-183
23rd	Liver	Philips. A comprehensive review of diagnosis and management of alcohol-associated hepatitis. SAGE Open Medicine 2024;12
22nd	Respiratory	Savale. Transplantation, bridging, and support technologies in pulmonary hypertension. Eur Respir J 2024;64(4):2401193
21st	Resuscitation	Endo. Acute lung injury and post-cardiac arrest syndrome: a narrative review. J Intensive Care 2024;12:32
20th	Sepsis	Borges. Organ crosstalk and dysfunction in sepsis. Ann Intensive Care 2024;14:147
19th	Circulatory	Natarajan. Acute Lower Limb Ischemia—Etiology, Pathology, and Management. Int J Angiol 2020;29(3):168–174
18th	Neuro	Avola. Treatment-related reversible cerebral vasoconstriction syndrome. J Clin Med 2024;13(19):5930
17th	Airway	De Jong. How to improve intubation in the intensive care unit. Update on knowledge and devices. Intensive Care Med 2022;48;1287-1298
16th	Respiratory	Cammarota. Advanced Point-of-care Bedside Monitoring for Acute Respiratory Failure. Anesthesiology 2023;138:317–334
15th	Endocrine	Arno Téblick. Critical Illness-induced Corticosteroid Insufficiency: What It Is Not and What It Could Be. J Clin Endocrinol Metab 2022;107(7):2057-2064
14th	Nutrition	Anderson. Impact of Obesity in Critical Illness. Chest. 2021;160(6):2135-2145
13th	Respiratory	Howroyd. Ventilator-associated pneumonia: pathobiological heterogeneity and diagnostic challenges. Nat Commun 2024;15:6447
12th	Resuscitation	Horn. Diagnosis and management of seizures and myoclonus after cardiac arrest. Eur Heart J Acute Cardiovasc Care 2023;12(8):525-531
11th	Circulatory	Kimman. Mechanical Support in Early Cardiogenic Shock: What Is the Role of Intra-aortic Balloon Counterpulsation? Curr Heart Fail Rep 2020;17(5):247-260
10th	Neuro	Meyfroidt. Management of moderate to severe traumatic brain injury: an update for the intensivist. Intensive Care Med 2022;48:649–666
9th	Haematology	Retter. Consumptive coagulopathy in the ICU. Hematology Am Soc Hematol Educ Program 2023;2023(1):754-760
8th	Respiratory	Walter. Invasive Mechanical Ventilation. South Med J 2018;111(12):746-753
7th	Circulatory	Avvedimento. Acute advanced aortic stenosis. Heart Fail Rev 2023;28:1101-1111
6th	Trauma	Savoia. Focused Assessment with Sonography for Trauma (FAST). J Med Ultrasound 2023;31(2):101-106
5th	Obstetrics	Conti. Pregnancy Arrhythmias: Management in the Emergency Department and Critical Care. J Clin Med 2024;13(4):1095
4th	Liver	Jagdish. Pathophysiology and management of liver cirrhosis: from portal hypertension to acute-on-chronic liver failure. Front Med 2023;10:1060073
3rd	Nutrition	Krutkyte. Refeeding Syndrome: A Critical Reality in Patients with Chronic Disease. Nutrients 2022;14(14):2859
2nd	Respiratory	Guérin. Prone position in ARDS patients: why, when, how and for whom. Intensive Care Med 2020;46(12):2385-2396
1st	Neuro	Benghanem. Brainstem dysfunction in critically ill patients. Crit Care 2020;24:5