CCR-Newsletter-BannerNewsletter 419  |  December 22nd 2019

Journal Watch  |  Newsletters  |  CCR Meeting 2020  |  CCR18 BookPodcast  |  Hot Articles  |  Topic of the Week  |  Reviews  |  Top 100 Studies  |  Guidelines  |  Journals

 

PEPTIC Session Programme
 

Merry Christmas

Welcome to the 419th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on comparing rocuronium with succinylcholine on endotracheal intubation in out-of-hospital rapid sequence intubation & inhaled amikacin adjunctive to intravenous standard-of-care antibiotics in mechanically ventilated patients with Gram-negative pneumonia; systematic reviews and meta analyses on adverse events during intrahospital transport of critically ill children & whether norepinephrine or vasopressin should be discontinued first in septic shock; and observational studies on vitamin E acetate in bronchoalveolar-lavage fluid associated with EVALI & the association of prehospital plasma transfusion with survival in trauma patients with hemorrhagic shock.

There are also narrative reviews on fluid administration strategies in traumatic brain injury & comparison between thromboelastography and thromboelastometry; editorials on controversies surrounding prevention of ventilator-associated pneumonia & anaesthetic management of the airway after blunt and penetrating neck injury; and commentaries on clinically meaningful benefit in clinical research & organising international research in critical care medicine.

This week's Topic of the Week is the PEPTIC trial, starting with a paper on the risks and benefits of stress ulcer prophylaxis in tomorrow's Paper of the Day.

If you only have time to read one review article this week, try this one on acute kidney injury from sepsis.

 

Research

Review Articles

Neurological

Circulatory

Gastrointestinal

Hepatobiliary

Renal

Haematological

Sepsis

Trauma

Toxicology

Perioperative

Miscellaneous

CCR20 Meeting

Now in it's 8th year, the Critical Care Reviews Meeting brings the chief investigators for the best critical care trials of the previous year to Titanic, Belfast, to discuss their studies. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice. It's not just about specific trials though; for 2020, we have a distinguished panel of trialists, methodologists, statisticians and clinicians provide insight into the mysteries of clinical trial interpretation, as well as a panel discission on the proposed MEGA-ROX trial, potentially a game changer for critical care trials. We are delighted to have the opportunity to conduct a one-on-one interview with the editor-in-chief of JAMA, Prof Howard Bauchner, in discussion with Prof Marion Campbell. As usual, we eound off the formal programme with the annual honorary John Hinds Lecture, to be delivered by Prof Kathryn Maitland, entitled "A Higher Calling: Two Decades of Emergency Research in Africa", and finish the meeting with the incredibly popular "Informal Chat", where the faculty and delegates congregate in the bar and an enormous, meandering discussion about all things critical care takes place.

For CCR20, we are hosting 3 major trial results presentations, PEPTIC, 65 & VITAMINS, plus the IHME SEPSIS study results, as well as discussing 9 of the best trials from 2019 - COACT, TRACT, ICU-ROX, SPICE III, BiRDS, ROSE, CITRIS-ALI, SEPSIS-ACT & HYPERION

Based on our feedback from last year, we've reverted to keeping everyone on the same floor during breaks. In addition, we will also provide a sleeping area for those post-call to rest for a few hours as needed. As before, we are offering free childcare and a baby feeding area, where the meeting will live streamed. All dietary requirements are catered for also. Please get in touch if you have any specific needs. We sold out last year, so please don't delay if you want to attend. As usual, CPD points will be applied for in due course.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.


Until next week

Rob

Supported by the Health Research Board

ICCCTN logo Circular Text 100x100

Search