CCR-Newsletter-BannerNewsletter 414  |  November 19th 2019

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Welcome to the 414th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on simvastatin for pneumonia & colchicine after myocardial infarction; systematic reviews and meta analyses on lung recruitment in ARDS & methods of temperature management in comatose patients post cardiac arrest; and observational studies on how impaired right ventricular performance is associated with adverse outcome after hypoxic ischemic encephalopathy & how host-response subphenotypes offer prognostic enrichment in ARDS.

There are also guidelines on awake tracheal intubationtype 2 myocardial infarction and acute nonischemic myocardial injury & the latest 2019 ILCOR guidance on cardiopulmonary resuscitation and emergency cardiovascular care. In addition, there are narrative reviews on AKI and hepatorenal syndrome & early brain injury after poor-grade subarachnoid hemorrhage; editorials on whether critical care patients hibernate & if a microbiologist consultant should attend daily ICU rounds; and commentaries on ‘less is more’ in modern icu & a triology of papers on the ADRENAL & APROCCHSS.

Continuing our focus on the trials being presented at the Critical Care Reviews Meeting 2020, this week's Topic of the Week is the TRACT trial, investigating treatment and transfusion thresholds in severe anaemia in African children. The first paper yesterday was a general review on malaria, a major cause of anaemia in African children. We continue with a slightly old paper, reviewing the management of malaria in the intensive care unit, in today's Paper of the Day.

If you only have time to read one review article this week, try this one on SIADH and cerebral salt-wasting syndromes in neurological patients.

 

Research

Guidelines

Review Articles

Neurological

Respiratory

Gastrointestinal

Hepatobiliary

Renal

Sepsis

Miscellaneous

CCR20 Meeting

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Now in it's 8th year, the Critical Care Reviews Meeting brings the chief investigators for the best critical care trials of the previous year to Titanic, Belfast, to discuss their studies. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice. It's not just about specific trials though; for 2020, we have a distinguished panel of trialists, methodologists, statisticians and clinicians provide insight into the mysteries of clinical trial interpretation. We also have the annual honorary John Hinds Lecture, to be delivered by Prof Kathryn Maitland, entitled "A Higher Calling: Two Decades of Emergency Research in Africa", and finish the meeting with the incredibly popular "Informal Chat", where the faculty and delegates congregate in the bar and an enormous, meandering discussion about all things critical care takes place.

Based on our feedback from last year, we've reverted to keeping everyone on the same floor during breaks. In addition, we will also provide a sleeping area for those post-call to rest for a few hours as needed. As before, we are offering free childcare and a baby feeding area, where the meeting will live streamed. All dietary requirements are catered for also. Please get in touch if you have any specific needs. We sold out last year, so please don't delay if you want to attend. As usual, CPD points will be applied for in due course.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.


Until next week

Rob

Supported by the Health Research Board

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Neurological

Respiratory

Gastrointestinal

Hepatobiliary

Renal

Sepsis

Miscellaneous

Burlacu. Challenging the supremacy of evidence-based medicine through artificial intelligence: the time has come for a change of paradigms. Nephrol Dial Transplant 2019;epublished November 7th

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