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CCR-Newsletter-BannerNewsletter 399  |  August 4th 2019

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Welcome to the 399th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are two papers reporting the TRACT RCT (being discussed at CCR20), as well as the long awaited publication of the PHARLAP RCT, which we hosted the results presentation of at CCR19 (the video should be out very soon); systematic reviews and meta analyses on liberal versus restrictive red blood cell transfusion strategy in sepsis or septic shock & functional hemodynamic tests; and observational studies reporting of the core outcome set for critical care ventilation trials & vitamin A deficiency in critically ill children with sepsis. There are also guidelines on procalcitonin-guided antibiotic stewardship & acute liver failure; narrative reviews on perioperative haemodynamic monitoring & antibiotic stewardship in the ICU; and commentaries on less monitoring and diagnostic testing & pulmonary complications in liver disease

This week's Topic of the Week is CO2-derived variables for hemodynamic management in critically ill patients, starting with a paper on how CO2-derived indices can guide resuscitation in critically ill patients in tomorrow's Paper of the Day.

If you only have time to read one review article this week, try this one on intracranial pressure monitoring.

Critical Care Reviews Meeting 2020

The big news this week is the addition of the TRACT trial to CCR20. This trial investigates transfusion and treatment of severe anaemia in African children and will be presented by Prof Kathryn Maitland, the chief investigator for this exception programme of emergency research in East Africa. We are honoured to also have Prof Maitland deliver the annual honorary John Hinds Lecture at CCR20, entitled "A Higher Calling: Two Decades of Emergency Research in Africa".



Review Articles












CCR20 Meeting

CCR20 010819 Widget

Now in it's 8th year, the Critical Care Reviews Meeting brings the chief investigators for the best critical care trials of the previous year to Titanic, Belfast, to discuss their studies. We aim to decide whether these trials are sufficiently robust to support their findings and if we should consider changing practice on the basis of them. To help in this endeavour we invite world leading experts to provide independent editorial overviews and have panel discussions to delve deep into the specifics of each trial. In addition, we also have detailed discussions on research methodology, to encourage critical thinking about the scientific findings which form the basis of our clinical practice. It's not just about specific trials though; for 2020, we have a distinguished panel of trialists, methodologists, statisticians and clinicians provide insight into the mysteries of clinical trial interpretation. We also have the annual honorary John Hinds Lecture, to be delivered by Prof Kathryn Maitland, entitled "A Higher Calling: Two Decades of Emergency Research in Africa", and finish the meeting with the incredibly popular "Informal Chat", where the faculty and delegates congregate in the bar and an enormous, meandering discussion about all things critical care takes place.

Based on our feedback from last year, we've reverted to keeping everyone on the same floor during breaks. In addition, we will also provide a sleeping area for those post-call to rest for a few hours as needed. As before, we are offering free childcare and a baby feeding area, where the meeting will live streamed. All dietary requirements are catered for also. Please get in touch if you have any specific needs. We sold out last year, so please don't delay if you want to attend. As usual, CPD points will be applied for in due course.

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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