Welcome to the 391st Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are two randomised controlled trials on PEEP, one on intraoperative high PEEP with recruitment maneuvers & the other on PEEP and postoperative atelectasis; systematic reviews and meta analyses on physical therapy during ECMO & oxygenation and clinical outcomes to inform oxygen targets in critically ill trauma patients; and observational studies on the ongoing Ebola epidemic in Congo & survival in out-of-hospital cardiac arrest after standard CPR or chest compressions only.
There are also guidelines on acute-on-chronic liver failure & oesophageal emergencies; narrative reviews on rapid response systems & echocardiography in the management of VA ECMO; editorials on oxygen therapy & interventions to improve CPR; and a commentary on the role of the host response in influenza pneumonitis.
This week's Topic of the Week is one I've wanted to cover for a while and is based on a fantastic series on the evaluation of scientific publications from the German journal Deutsches Ärzteblatt International, starting with a paper on critical appraisal of scientific articles in today's Paper of the Day.
If you only have time to read one review article this week, try this one on atypical hemolytic uremic syndrome.
- Full Text: Writing Committee for the PROBESE Collaborative Group of the PROtective VEntilation Network (PROVEnet) for the Clinical Trial Network of the European Society of Anaesthesiology. Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients. A Randomized Clinical Trial. JAMA 2019;epublished June 3rd
- Full Text: Song. XueBiJing Injection Versus Placebo for Critically Ill Patients With Severe Community-Acquired Pneumonia. A Randomized Controlled Trial. Crit Care Med 2019;epublished June 3rd
- Full Text: de Azevedo. Optimized calorie and high protein intake versus recommended caloric-protein intake in critically ill patients: a prospective, randomized, controlled phase II clinical trial. Rev Bras Ter Intensiva 2019;epublished May 23rd
- Abstract: Östberg. Positive End-expiratory Pressure and Postoperative Atelectasis: A Randomized Controlled Trial. Anesthesiology 2019;epublished May 14th
- Abstract: Rathi. Variability in triage practices for critically ill cancer patients: A randomized controlled trial. J Crit Care 2019;53:18-24
- Full Text: Ferreira. Safety and potential benefits of physical therapy in adult patients on extracorporeal membrane oxygenation support: a systematic review. Rev Bras Ter Intensiva 2019;epublished May 13th
- Full Text: Seccombe. Assessing Fluid Resuscitation in Adults with Sepsis Who Are Not Mechanically Ventilated: a Systematic Review of Diagnostic Test Accuracy Studies. Journal of General Internal Medicine 2019;epublished May 31st
- Full Text: Becker. Association of Communication Interventions to Discuss Code Status With Patient Decisions for Do-Not-Resuscitate Orders. A Systematic Review and Meta-analysis. JAMA Netw Open 2019;2(6):e195033
- Abstract: Douin. Systematic Review of Oxygenation and Clinical Outcomes to Inform Oxygen Targets in Critically Ill Trauma Patients. J Trauma Acute Care Surg 2019;epublished May 30th
- Full Text: Kalenga. The Ongoing Ebola Epidemic in the Democratic Republic of Congo, 2018–2019. N Engl J Med 2019;epublished May 29th
- Full Text: Valley. Intensive care use and mortality among patients with ST elevation myocardial infarction: retrospective cohort study. BMJ 2019;365:l1927
- Abstract: Myles. Importance of intraoperative oliguria during major abdominal surgery: findings of the Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery trial. Br J Anaesth 2019;122(6):726–733
- Full Text: Riva. Survival in out-of-hospital cardiac arrest after standard cardiopulmonary resuscitation or chest compressions only before arrival of emergency medical services: nationwide study during three guideline periods. Circulation 2019;139:2600–2609
- Abstract: Tjepkema-Cloostermans. Outcome Prediction in Postanoxic Coma With Deep Learning. Crit Care Med 2019;epublished June 3rd
- Abstract: McNicholas. Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome. A Secondary Analysis of a Multicenter Observational Study (LUNG-SAFE). Crit Care Med 2019;epublished May 31st
- Full Text: Haines. Key mechanisms by which post-ICU activities can improve in-ICU care: results of the international THRIVE collaboratives. Intensive Care Med 2019;epublished June 4th
- Full Text: Murugan. Association of Net Ultrafiltration Rate With Mortality Among Critically Ill Adults With Acute Kidney Injury Receiving Continuous Venovenous HemodiafiltrationA Secondary Analysis of the Randomized Evaluation of Normal vs Augmented Level (RENAL) of Renal Replacement Therapy Trial. JAMA Netw Open 2019;2(6):e195418
- Full Text: Buitinck. The ecological effects of selective decontamination of the digestive tract (SDD) on antimicrobial resistance: a 21-year longitudinal single-centre study. Critical Care 2019;23:208
- Full Text: Abe. In-hospital mortality associated with the misdiagnosis or unidentified site of infection at admission. Critical Care 2019;23:202
- Full Text: Martucci. Trying to identify who may benefit most from future vitamin D intervention trials: a post hoc analysis from the VITDAL-ICU study excluding the early deaths. Critical Care 2019;23:200
- Abstract: Stohl. Impact of triage-to-admission time on patient outcome in European intensive care units: A prospective, multi-national study. J Crit Care 2019;53:11-17
- Kuramatsu. Reversal of oral anticoagulation in patients with acute intracerebral hemorrhage. Critical Care 2019;23:206
- Beez. Decompressive craniectomy for acute ischemic stroke. Critical Care 2019;23:209
- Park. Prevention and management of delirium in critically ill adult patients in the intensive care unit: a review based on the 2018 PADIS guidelines. Acute Crit Care 2019;34(2):117-125
- Sinha. Wernicke Encephalopathy—Clinical Pearls. Mayo Clin Proc 2019;94(6):1065–1072
- Bailleul. Role of echocardiography in the management of veno-arterial extra-corporeal membrane oxygenation patients. J Emerg Crit Care Med 2019;3:25
- Cho. Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting for the Treatment of Left Main Coronary Artery Disease. Korean Circ J 2019;49(5):369-383
- Gevaert. Heart Failure With Preserved Ejection Fraction: A Review of Cardiac and Noncardiac Pathophysiology. Front Physiol 2019;10:638
- Tonolini. A closer look at the stoma: multimodal imaging of patients with ileostomies and colostomies. Insights into Imaging 2019;10:41
- Catena. Bowel obstruction: a narrative review for all physicians. World J Emerg Surg 2019;14:20
- Berger. Atypical hemolytic uremic syndrome: a syndrome in need of clarity. Clinical Kidney Journal 2019;12(3):338–347
- Centeno. Anti-Xa assays: What is their role today in antithrombotic therapy? Cleveland Clinic Journal of Medicine 2019;86(6):417-425
- Lesho. The Slow-Motion Catastrophe of Antimicrobial Resistance and Practical Interventions for All Prescribers. Mayo Clin Proc 2019;94(6):1040–1047
- Cortés-Penfield. The History of Antibiotic Treatment of Osteomyelitis. Open Forum Infectious Diseases 2019;6(5):ofz181
- Ross. The ex vivo human lung: research value for translational science. JCI Insight 2019;4(11)
- Kim. Two-photon intravital imaging of leukocyte migration during inflammation in the respiratory system. Acute Crit Care 2019;34(2):101-107
- Hesselink. Neutrophil heterogeneity and its role in infectious complications after severe trauma. World Journal of Emergency Surgery 2019;14:24
- Chang. Sepsis and septic shock: endothelial molecular pathogenesis associated with vascular microthrombotic disease. Thrombosis Journal 2019;17:10
- Chalkias. Interventions to improve cardiopulmonary resuscitation: a review of meta-analyses and future agenda. Critical Care 2019;23:210
- Vergano. ELS (Ethical Life Support): a new teaching tool for medical ethics. Critical Care 2019;23:204
- Anonymous. Plan S: the final cut. Lancet 2019;93(10188):2276
- Girardis. What’s new in oxygen therapy? Intensive Care Med 2019;epublished May 14th
- Rawlinson. New preprint server for medical research. BMJ 2019;365:l2301
- Janvilisri. Alternative Therapeutic Approaches For Multidrug Resistant Clostridium difficile. Front Microbiol 2019;10:1216
- Tang. Understanding the role of host response in influenza pneumonitis. Intensive Care Med 2019;epublished April 24th
- Fred. The SASH Phenomenon: Calling Attention to the Natural History of Diseases. Texas Heart Institute Journal 2019;46(2):92-92
- Reisner. Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines, Executive Summary. Neurosurgery 2019;epublished June 7th
- Ihle. Confirmation of brain death on VA-ECMO should mandate simultaneous distal arterial and post-oxygenator blood gas sampling. Intensive Care Med 2019;epublished May 16th
- Cortegiani. Effect of high-flow nasal therapy on dyspnea, comfort, and respiratory rate. Critical Care 2019;23:201
- Iner. Short-term assist devices in postcardiotomy cardiogenic shock. Critical Care 2019;23:199
- Hoversten. 47-Year-Old Man With Pancytopenia and Fever. Mayo Clin Proc 2019;94(6):1073–1078
- Lundstrom. 57-Year-Old Woman With Dyspnea and Rash. Mayo Clin Proc 2019;94(6):1079–1083
- Vinnakota. 57-Year-Old Man With Vertigo. Mayo Clin Proc 2019;94(6):e73–e79
- McLaughlin. Disseminated invasive aspergillosis in an immunocompetent patient. Cleve Clin J Med 2019;86(6):369-370
- Migdady. A 69-year-old woman with double vision and lower-extremity weakness. Cleve Clin J Med 2019;86(6):374-379
- Au. Clot formation between the ECMO catheter and the reperfusion catheter in a patient supported by peripheral VA-ECMO. Intensive Care Med 2019;epublished June 3rd
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week
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