Critical Care Reviews Meeting 2019 Video
Welcome to the 381st Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials on sustained inflations vs intermittent positive pressure ventilation in extremely preterm infants & intramyocardial injection of mesenchymal precursor cells in patients with LVADs for advanced heart failure; systematic reviews and meta analyses on pleural effusion drainage in the ICU & socioeconomic position and health outcomes following critical illness; and observational studies on REBOA in civilian trauma & time to epinephrine treatment in children with traumatic out-of-hospital cardiac arrest. The fifth edition of the European guideline on the management of major bleeding and coagulopathy following trauma is out this week, as is a French guideline on the optimization of the treatment with beta-lactam antibiotics in critically ill patients.
There are also narrative reviews on intracerebral hemorrhage, sepsis: the evolution in definition, pathophysiology, and management, & dysphagia in the ICU; editorials on direct oral anticoagulants for venous thromboembolism prophylaxis in critically ill patients & the TARGET trial; and a commentary on norepinephrine, more than a vasopressor;
This week's Topic of the Week is a selection of 7 papers from Intensive Care Medicine's series on "Ten Tips for the Management of...", starting with a paper on ten tips for the intensive care management of transplanted lung patients in tomorrow's Paper of the Day.
If you only have time to read one review article this week, try this one on rationalizing antimicrobial therapy in the ICU.
Critical Care Reviews Meeting 2020
In meeting news, registration for the Critical Care Reviews Meeting 2020 opens next Sunday April 7th. The initial group of trials to be presented and attending faculty will be announced. The meeting is on Thursday & Friday, January 16th & 17th, in Titanic, Belfast, Northern Ireland. Check out the short video above if you haven't been to the meeting yet.
- Abstract: Kirpalani. Effect of Sustained Inflations vs Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants. The SAIL Randomized Clinical Trial (SAIL). JAMA 2019;321(12):1165-1175
- Abstract: Yau. Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure. A Randomized Clinical Trial. JAMA 2019;321(12):1176-1186
- Abstract: Macdonald. Bolus therapy with 3% hypertonic saline or 0.9% saline in emergency department patients with suspected sepsis: A pilot randomised controlled trial. J Crit Care 2019;epublished March 28th
- Abstract: Burns. Frequency of Screening for Weaning From Mechanical Ventilation. Two Contemporaneous Proof-of-Principle Randomized Controlled Trials. Crit Care Med 2019;epublished March 27th
- Abstract: Nasi. Early Manipulation of Arterial Blood Pressure in Acute Ischemic Stroke (MAPAS): Results of a Randomized Controlled Trial. Neurocritical Care 2019;30(2):372-379
- Abstract: Vetrugno. Utility of pleural effusion drainage in the ICU: An updated systematic review and META-analysis. J Crit Care 2019;epublished March 28th
- Abstract: Jones. Socioeconomic Position and Health Outcomes Following Critical Illness. A Systematic Review. Crit Care Med 2019;epublished March 27th
- Abstract: Shemilt. Prognostic Value of Glial Fibrillary Acidic Protein in Patients With Moderate and Severe Traumatic Brain Injury. A Systematic Review and Meta-Analysis. Crit Care Med 2019;epublished March 19thA Systematic Review and Meta-Analysis. Crit Care Med 2019;epublished March 19th
- Abstract: Pettenuzzo. Effect of Neurally Adjusted Ventilatory Assist on Patient-Ventilator Interaction in Mechanically Ventilated Adults. A Systematic Review and Meta-Analysis. Crit Care Med 2019;epublished March 15th
- Full Text: Lin. Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest. Critical Care 2019;23:101
- Abstract: Joseph. Nationwide Analysis of Resuscitative Endovascular Balloon Occlusion of the Aorta in Civilian Trauma. JAMA Surg 2019;epublished March 20th
- Abstract: Harahsheh. Thromboelastography Predicts Thromboembolism in Critically Ill Coagulopathic Patients. Crit Care Med 2019;epublished March 27th
- Abstract: Hammond. Effects of norepinephrine and vasopressin discontinuation order in the recovery phase of septic shock: a systematic review and individual patient data meta-analysis. Pharmacotherapy 2019;epublished March 20th
- Full Text: Ni. The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis. Critical Care 2019;23:99
- Jewer. Supplemental perioperative intravenous crystalloids for postoperative nausea and vomiting.Cochrane Database of Systematic Reviews 2019, Issue 3. Art. No.: CD012212
- Felder. Prolonged thromboprophylaxis with low molecular weight heparin forabdominal or pelvic surgery.Cochrane Database of Systematic Reviews 2019, Issue 3. Art. No.: CD004318
- Tingle. Machine perfusion preservation versus static cold storage fordeceased donor kidney transplantation.Cochrane Database of Systematic Reviews 2019, Issue 3. Art. No.: CD011671
- The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition. Critical Care 2019;23:98
- Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique—SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d’Anesthésie et Réanimation—SFAR). Critical Care 2019;23:104
- Garg. Recent advances in spontaneous intracerebral hemorrhage. F1000Research 2019, 8(F1000 Faculty Rev):302
- Li. Current progress in searching for clinically useful biomarkers of blood–brain barrier damage following cerebral ischemia. Brain Circ 2018;4:145-52
- Fisher. Evaluating patients for thrombectomy. Brain Circ 2018;4:153-9
- Wang. Prehospital stroke care, a narrative review. Brain Circ 2018;4:160-4
- Arya. Brain–gut axis after stroke. Brain Circ 2018;4:165-73
- Amzulescu. Myocardial strain imaging: review of general principles, validation, and sources of discrepancies. European Heart Journal - Cardiovascular Imaging 2019;jez041
- Maciejewski. High flow oxygen therapy in intensive care and anaesthesiology. Anaesthesiol Intensive Ther 2019;51(1):41-50
- Zielińska. Oxygen therapy with high-flow nasal cannulas in children with acute bronchiolitis. Anaesthesiol Intensive Ther 2019;51(1):51-55
- Bhamani. Lifting the fog in intermediate-risk (submassive) PE: full dose, low dose, or no thrombolysis? F1000Research 2019, 8(F1000 Faculty Rev):330
- Wong. Fibreoptic intubation in airway management: a review article. Singapore Med J 2019;60(3):110-118
- Soldati. Ultrasound patterns of pulmonary edema. Ann Transl Med 2019;7(Suppl 1):S16
- Zuercher. Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management. Critical Care 2019;23:103
- Pluta. Thrombocytopenia: the most frequent haemostatic disorder in the ICU. Anaesthesiol Intensive Ther 2019;51(1):56-63
- Timsit. Rationalizing antimicrobial therapy in the ICU: a narrative review. Intensive Care Med 2019;45(2):172–189
- Gyawali. Sepsis: The evolution in definition, pathophysiology, and management. SAGE Open Med 2019;7:2050312119835043
- Kotfis. Balancing sedation and ICU delirium management for better patient outcomes. Anaesthesiol Intensive Ther 2019;51(1):1-3
- Delaere. Tracheal transplantation. Intensive Care Med 2019;45:391–39
- Jaber. 10 tips for intensive care management of transplanted liver patients. Intensive Care Med 2019;45:377–379
- Poole. Prediction of optimal outcomes in organ transplantation. Intensive Care Med 2019;45:367–370
- Courtright. Focus on ethics and palliative care in the intensive care unit. Intensive Care Med 2019;epublished March 25th
- Bertoletti. Direct oral anticoagulants for venous thromboembolism prophylaxis in critically ill patients: where do we go from here? Intensive Care Med 2019;epublished March 25th
- Yehya. Pediatric ARDS biomarkers: missing the random forest for the trees. Critical Care 2019;23:97
- Young. What should we target after TARGET? Crit Care Resus 2018;20(4):252-253
- Espinoza. Norepinephrine, more than a vasopressor. Ann Transl Med 2019;7(Suppl 1):S25
- Pugh. Electronic health records, physician workflows and system change: defining a pathway to better healthcare. Ann Transl Med 2019;7(Suppl 1):S27
- Chambers. Nephron repair: powered by anaerobic energy metabolism. Ann Transl Med 2019;7(Suppl 1):S28
- O’Neill. Retooling Nephrology with Ultrasound. Clin J Am Soc Nephrol 2019;epublished March 27th
- van Stigt. Beriberi in the ICU: remarkable shock reversal with thiamine. Neth J Crit Care March 2019;27(2):93-6
- Kok. A patient with acute bilateral paralysis of the legs. Neth J Crit Care March 2019;27(2):97-8
- McBride. Dabigatran Toxicity in Acute Kidney Injury: Hemodialysis and Idarucizumab. Kidney Int Rep 2019;4(3):500–504
- Pugh. Cyclophosphamide-Induced Lung Injury. Kidney Int Rep 2019;4(3):
- Woo. Isolated right ventricle infarction. Singapore Med J 2019; 60(3):124-129
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week
Supported by the Health Research Board