CCR-Newsletter-BannerNewsletter 333  |  April 29th 2018

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CCR19 Twitter Launch#CCR19 Registration is Open


Welcome to the 333rd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. It's a packed issue this week, whose highlights are randomised controlled trials on oxygen titration after resuscitation from out-of-hospital cardiac arrest, rapid response systems in acute hospitals, & tenecteplase versus alteplase before thrombectomy for ischemic stroke; meta analysis on early goal-directed therapy in sepsis & viscoelastic haemostatic assays in non-cardiac surgical settings, an observation study on nutritional therapy in Australian and New Zealand ICUs; plus guidelines & statements on hypovolemia in sepsis & scientific knowledge gaps and clinical research priorities for CPR and emergency cardiovascular care. There are also narrative reviews on rethinking current resuscitation strategies, mechanically ventilating the severe asthmatic & tissue oedema in sepsis; as well as commentaries on direct oral anticoagulants & time for a new definition of death?

If you only have time to read one paper this week, try this meta analysis on liberal versus conservative oxygen therapy in acutely ill adults. With ICU-ROX (due to be discussed at #CCR19), as well as the HOT-ICU and Oxy-PICU trials currently ongoing, this meta analysis provides lots to think about.

We continue this theme of oxygenation targets in this week's Topic of the Week, starting with a paper on the medical use of oxygen: a time for critical reappraisal in tomorrow's Paper of the Day.



Review Articles














Belfast, 18-19th January 2019

SMACC 2019

SMACC Sydney

Sydney, 26-29th March 2019


Women in ICM

London, February 6th

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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