Welcome to the 212th Critical Care Reviews Newsletter, the first newsletter of 2016. It's been another quiet week for research, but there are plenty of other articles to read. The highlights of this week's newsletter are papers on echocardiography in acute heart failure, an update in acute pancreatitis, and drug-induced metabolic acidosis, as well as recently made open access articles from the major journals, on respiratory complications of organophosphate poisoning and acute cor pulmonale in ARDS. There is also a guideline on renal replacement therapy from the French Intensive Care Society.
It's now less than four week's to the most contemporary critical care meeting around, discussing the biggest studies of 2015 with their Chief Investigators. If you haven't yet booked your place at the Critical Care Reviews Meeting 2016 in Belfast on Friday, January 29th, then don't delay too long, or you might miss out.
- Full Text: Venkatesh. Incidence and outcome of adults with diabetic ketoacidosis admitted to ICUs in Australia and New Zealand. Critical Care 2015;19:451
- Abstract: Greer. Variability of Brain Death Policies in the United States. JAMA Neurol 2015;epublished December 28th
- Abstract: Lauridsen. Acute kidney injury treated with renal replacement therapy and 5-year mortality after myocardial infarction-related cardiogenic shock: a nationwide population-based cohort study. Critical Care 2015;19:452
- Full Text: Robert. Influence of ICU-bed availability on ICU admission decisions. Annals of Intensive Care 2015;5:55
- Abstract: Vossen. Doripenem treatment during continuous renal replacement therapy. Antimicrob Agents Chemother 2015;epublished December 28th
- Abstract: Mongodi. Lung Ultrasound for Early Diagnosis of Ventilator-Associated Pneumonia. Chest 2015;epublished December 31st
- Abstract: Stefan. Hospitals Patterns of Use of Noninvasive Ventilation in Patients with Asthma Exacerbation (Hospitals Use of Ventilation in Asthma). Chest 2015;epublished December 31st
- Abstract: De Pascale. Clinical and microbiological outcome in septic patients with extremely low 25-hydroxyvitamin D levels at initiation of critical care. Clin Microbiol Infect 2015;epublished December 22nd
- Abstract: Chiumello. Lung Recruitment Assessed by Respiratory Mechanics and by CT Scan: What is the Relationship? Am J Respir Crit Care Med 2015;epublished December 23rd
- Tülü. Remote ischemic preconditioning in the prevention of ischemic brain damage during intracranial aneurysm treatment (RIPAT): study protocol for a randomized controlled trial. Trials 2015;16:594
- Mpoya. Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial. Trials 2015;16:593
- Rafols. Control of the brain microcirculation following traumatic brain injury and stroke. Brain Circ 2015;1:146-59
- Ellens. The use of barbiturate-induced coma during cerebrovascular neurosurgery procedures: A review of the literature. Brain Circ 2015;1:140-5
- Jankovic. Monitoring the Neuromuscular Blockade: Recent Developments and Recommendation for its Routine Implementations. EC Anaesthesia 2015;2(4):152-161
- Papadimitriou. Echocardiography in Acute Heart Failure: Current Perspectives. Journal of Cardiac Failure 2016;22(1):82-94
- Kitai. Recent advances in treatment of heart failure. F1000Research 2015;4(F1000 Faculty Rev):1475
- Victor. Extracorporeal membrane oxygenation. Echo Res Pract 2015;2(2):D1–D11
- Benes. Fluid Therapy: Double-Edged Sword during Critical Care? BioMed Research International 2015;2015:729075
- Kitzman. Vascular Dysfunction in Heart Failure with Preserved Ejection Fraction. Journal of Cardiac Failure 2016;22(1):12–16
- Garbi. Quantitative mitral valve anatomy and pathology. Echo Res Pract 2015;2(3):R63–R72
- Pasupathy. The What, When, Who, Why, How and Where of Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA). Circulation Journal 2016;80(1):11-16
- Parikh. Mode of Death After Acute Heart Failure Hospitalization – A Clue to Possible Mechanisms. Circulation Journal 2016;80(1):17-23
- Dudzinski. Multidisciplinary Pulmonary Embolism Response Teams. Circulation 2016;133:98-103
- Sharkey. Update in Perioperative Maternal Intensive Care. EC Anaesthesia 2015;2(4):178-186
- Janisch. Recent Advances in Managing Acute Pancreatitis. F1000Research 2015;4(F1000 Faculty Rev):1474
- Huang. Techniques for Abdominal Wall Closure after Damage Control Laparotomy: From Temporary Abdominal Closure to Early/Delayed Fascial Closure—A Review. Gastroenterology Research and Practice 2016;2016:2073260
- Graham. Advances in upper gastrointestinal endoscopy. F1000Research 2015;4(F1000 Faculty Rev):1457
- Iruzubieta. The Need for Biomarkers in Diagnosis and Prognosis of Drug-Induced Liver Disease: Does Metabolomics Have Any Role? BioMed Research International 2015;2015:386186
- Pham. Drug-Induced Metabolic Acidosis. F1000Research 2015;4(F1000 Faculty Rev):1460
- Zampronio. Central mediators involved in the febrile response: effects of antipyretic drugs. Temperature;2(4):506-521
- Rogers. Recent Advances in Preventing Adverse Reactions to Transfusion. F1000Research 2015;4(F1000 Faculty Rev):1469
- Erdmann. Focused use of drug screening in overdose patients increases impact on management. Swiss Med Wkly 2015;145:w14242
- Irani. Management and Prevention of Anaphylaxis. F1000Research 2015;4(F1000 Faculty Rev):1492
- Kenndey. Immunology for Anaesthetists. Epublished December 30th, 2015. Anaesthesia Tutorial of the Week. World Federation of Societies of Anesthesiologists.
- Saleh. Implementation of enhanced recovery after surgery in pediatric cardiac practice: a synopsis. Ain-Shams J Anaesthesiol 2015;8:463-8
- Aziz. Sedation and analgesia after pediatric cardiac surgery. Ain-Shams J Anaesthesiol 2015;8:469-73
American Journal of Respiratory and Critical Care Medicine
- Hulse. Respiratory Complications of Organophosphorus Nerve Agent and Insecticide Poisoning. Implications for Respiratory and Critical Care. Am J Respir Crit Care Med 2014;190(12):1342-1354
- Ware. Transfusion-induced Lung Endothelial Injury: A DAMP Death? Am J Respir Crit Care Med 2014;190(12):1331-1332
- Brummel. Willie Sutton and the Future of Acute Respiratory Distress Syndrome Research. Am J Respir Crit Care Med 2015;191(1):10-11
- Lemaire. New European Regulation for Clinical Trials of Medicinal Products. Am J Respir Crit Care Med 2015;191(1):16-18
- Sorkness. Nature, Nurture, and Lung Volumes. Am J Respir Crit Care Med 2015;191(1):11-12
- Fan. An Official American Thoracic Society Clinical Practice Guideline: The Diagnosis of Intensive Care Unit–acquired Weakness in Adults. Am J Respir Crit Care Med 2014;190(12):1437-1446
- Repessé. Acute Cor Pulmonale in ARDS: Rationale for Protecting the Right Ventricle. Chest 2015;147(1):259-265
- Niederman. Managing Ventilator Complications in a “VACuum” of Data. Chest 2015;147(1):5-6
- Cardinal-Fernández. ARDS: Lessons Learned From the Heart. Chest 2015;147(1):7-8
- Davidson. The Association of Direct Thrombin Inhibitor Anticoagulants With Cardiac Thromboses. Chest 2015;147(1):21-24
- Cardenas-Garcia. A 75-Year-Old Woman With Fever and a Right Upper Lobe Pulmonary Mass. Chest 2015;147(1):e1-e4
- Kanai. Avoiding Vessel Laceration in Thoracentesis: A Role of Vascular Ultrasound With Color Doppler. Chest 2015;147(1):e5-e7
- Vakil. A 44-Year-Old Woman With Metabolic Acidosis, High Anion Gap, and Delayed Neurologic Deterioration. Chest 2015;147(1):e18-e21
- Soni. A 47-Year-Old Returning Traveler With Shock. Chest 2015;147(1):e8-e12
- Haddy. Coexisting Aortic Stenosis and Left Ventricular Outflow Tract Obstruction. Anesthesiology 2015;123:213
- Raghunathan. Confounders versus Mediators: An Important Distinction. Anesthesiology 2015;123:234
- Ertmer. High-molecular Hydroxyethyl Starch: Is More Data Still Needed? Anesthesiology 2015;123:234-235
- Kurz. In Reply. Anesthesiology 2015;123:235-236
Anesthesia & Analgesia
- Kopman. Laparoscopic Surgery and Muscle Relaxants: Is Deep Block Helpful? Anesth Analg 2015;120(1):51-58
- Feldman. Optimal Ventilation of the Anesthetized Pediatric Patient. Anesth Analg 2015;120(1):165-175
- Chui. Anesthetic Management of Patients Undergoing Intracranial Bypass Procedures. Anesth Analg 2015;120(1):193-203
- Leeson. Medical and Ethical Challenges During the First Successful Human Kidney Transplantation in 1954 at Peter Bent Brigham Hospital, Boston. Anesth Analg 2015;120(1):239-245
- Vinsonneau. Renal replacement therapy in adult and pediatric intensive care : Recommendations by an expert panel from the French Intensive Care Society (SRLF) with the French Society of Anesthesia Intensive Care (SFAR) French Group for Pediatric Intensive Care Emergencies (GFRUP) the French Dialysis Society (SFD). Ann Intensive Care 2015;5(1):58
- Ling. APSIC Guidelines for environmental cleaning and decontamination. Antimicrobial Resistance and Infection Control 2015;4:58
- ANZICS. Acute Pain Management: Scientific Evidence 2015
- Lorsomradee. From Macro to Microcirculation for Practical Perioperative Organ Protection: Perioperative Goal Directed Therapy. EC Anaesthesia 2015;2(4):148-151
- Tsujita. How Should We Treat Myocardial Infarction Patients With Multivessel Disease? – Staged Revascularization? Or Stent Them All Acutely? Circ J 2015;epublished December 25th
- Honore. Peri-operative fluid strategy and post-operative acute kidney injury in cardiac surgery patients: any role for pre-operative statin therapy? Critical Care 2015;19:453
- Various. Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. N Engl J Med 2015;373:2686-2687
- Various. Takotsubo (Stress) Cardiomyopathy. N Engl J Med 2015;373:2688-2691
Due to hugely successful previous events, the Critical Care Reviews Meeting 2016 has been moved to a brand new venue, the stunning, multi-million pound Titanic Centre, birthplace of RMS Titanic, As before, the meeting theme is to review the biggest studies of the previous year, with chief investigators present where possible to discuss their work in person. From Wellington, New Zealand, Dr Paul Young will talk on his studies SPLIT (saline versus plasmalyte) and HEAT (paracetamol for pyrexia control). Dr John Holcomb (Houston, USA) will review his mega trial PROPPR, evaluating blood product transfusion ratios in traumatic haemorrhage. Dr Anthony Gordon (London, England), will review his VANISH study, a multi-centre randomized controlled trial comparing vasopressin with noradrenaline, with or without hydrocortisone, for first-line vasopressor support in septic shock. Prof Tim Walsh (Edinburgh, Scotland) will review the ABLE study, including his ABLE UK component, evaluating age of transfused red cells, as well as RECOVER, a post-ICU rehab study. In addition, two of the most eminent intensivists in global critical care, Prof Jean-Louis Vincent (Brussels, Belgium) and Prof Luciano Gattinoni (Milan, Italy) will be on hand to discuss the significance of these findings. A new feature for the meeting is the John Hinds' Trauma Lecture, with Dr Brian Burns (Sydney HEMS, Australia) travelling across the world to deliver the inaugural presentation. It won't be all study discussion, with other elements to the meeting, including the spectacularly popular "Informal Chat", taking place that evening.
If you haven't yet attended this modern, niche meeting, then put the date Friday January 29th in your diary. Both delegate and speaker feedback from previous meetings has been incredibly positive, allowing the event to grow and attract some of the biggest names in critical care. The Titanic Centre is just minutes from Belfast City Airport, with a hotel within 3 minutes walking distance, and is a 20 minute walk from the city centre, including the Cathedral Quarter, Belfast's cultural centre full of great restaurants and pubs. Further details regarding delegate rate accommodation should be available in the next week or two. Talks are given in the setting of the rebuilt famous staircase from the great ship, while both the "Informal Chat" session and dinner overlook the floodlit slipways where Titanic and Olympic were launched. Ton finish a fantastic day, we have a pre-dinner talk from a colleague of mine, Mr Chris Andrews, on "My Great Great Uncle Thomas Andrews - The Man Who Built Titanic".
With some exciting new innovations planned, this new meeting promises to delivery on its burgeoning reputation. Don't wait too long before registering, as numbers are capped to keep this an intimate event. It is as strong a one day programme as you could possibly find. If you think your colleagues would find this event interesting, please circulate this information - this is a not-for-profit event, run in association with the Northern Ireland Intensive Care Society.
The next SMACC Conference is on June 13th to 16th, in Dublin, Ireland. Registration opened on October 28th, sold out in a few hours, and closed again. It opened again on December 2nd and sold out in just 15 minutes. Luckily, there is on further batch of tickets available on Wednesday February 3rd. With world leading academics and high profile clincians from the FOAMed critical care world, this conference fuses knowledge, dynamism and enthusiasm with an altruisitic desire to be the best we can be for the benefit of our patients. It's the most fun, modern critical care conference in the world. If you've been lucky enough to register for #smaccDUB, the presentations from SMACC Chicago, which are now online at Intensive Care Network, will give you an idea as to what to expect.
(Image from Wikimedia)
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week