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Newsletter 153 / November 9th 2014



Welcome to the 153rd Critical Care Reviews Newsletter, bringing you the best critical care research published in the past week, plus a wide range of free full text review articles, guidelines, commentaries, editorials, study critiques, correspondence and case reports from hundreds of clinical and scientific journals. It's a large newsletter this week, with the highlights being a report of a potential reversal agent for a new oral anticoagulant, a slightly different view from the East on the management of sepsis, with a sepsis guideline from the Japanese Society of Intensive Care Medicine, plus review articles on ARDS, resuscitative thoracotomy, severe sepsis and the critical care management of the patient with Ebola virus disease.

This week's Topic of the Week is prehospital critical care, starting with a paper on out-of-hospital traumatic cardiac arrest by Peter Sherren and the Sydney HEMS group, in tomorrow's Paper of the Day.

In other news, this week marks Armistice Day, with the Lancet publishing a themed series of papers on the medical legacy of the First World War. On a happier note, registration for SMACC Chicago open a few nights ago and promptly melted the SMACC servers. A limited number of early bird rates are/were available - check out the registration page for futher details.


Review Articles:  Clinical Non-Clinical  I  Basic Science  |  General Interest


Upcoming Meetings

Critical Care Reviews Meeting 2015

If you're interested in cutting edge critical care research, the 2015 Critical Care Reviews Meeting is the event for you. Being held on Friday January 23rd, at the Galgorm Resort and Spa, outside Belfast, Northern Ireland, a host of intensivists from near and far review the biggest studies of 2014, aiming to answer one question - should we implement the results of these studies? We'll discuss matters such as thrombolysis for intermediate-risk PE (PEITHO study), transfusion thresholds in sepsis (TRISS study), albumin in sepsis (ALBIOS study) and mechanical chest compression devices (LINC & CIRC studies).  In all, 13 RCTs will be discussed, including three of the major RCTs from last month's ESICM hot topics session, being presented by their Chief Investigators. There are also 5 review talks, including topics such as ECMO, airway management and neuroprognostication post cardiac arrest. The impressive list of speakers includes Clifford Deutschman (USA, past president of the Society of Critical Care Medicine), Niklas Nielsen (Sweden, CI for the TTM study), Eddy Fan (Canada, Medical Director of the Extracorporeal Life Support program at Toronto General Hospital.), Kathy Rowan (England, ICNARC Director & CI for CALORIES & ProMISe studies), Karin Amrein (Austria, CI for VITdAL-ICU), Danny McAuley (Belfast, CI for HARP-2 study), Eamon McCoy (Belfast, inventor of the McCoy Laryngoscope), and John Hinds (Craigavon, motor racing prehospitalist, anaesthetist & intensivist).

If you're a drive or short flight away, it would be great to have you come along. Travel on Thursday, attend the meeting on Friday and see some of the local landmarks over the weekend, before returning home on Sunday evening after a great winter break. On Saturday visit the North Coast: the World Heritage site Giants Causeway, Carrick-a-Rede rope bridge, Dunluce Castle and Bushmills Distillary, the oldest distillary in the world; while on Sunday experience Belfast: the new acclaimed Titanic Centre followed by a famous black taxi tour describing the troubled past of one of Europe's now most vibrant cities. The Galgorm Resort and Spa is one of Northern Ireland's premier hotels and is a 30 minute drive from Belfast International Airport.  Please feel free to contact me if you're thinking about making the trip - it would be great to hear from you.

The programme is available as a download, with further information at the meeting webpage. Online registration has opened, with registrations flooding in. As capacity is limited, don't wait to book your place and potentially miss out. If you think your colleagues would be interested in attending this contemporary niche meeting, please either forward this newsletter or the programme. This ia a not-for-profit meeting held in association with the Northern Ireland Intensive Care Society.

SMACC Chicago

The next SMACC conference will be held June 23rd to 26th, in Chicago, USA. Just like the Critical Care Reviews Meeting, this is a not-for-profit event, run by a team interested in sharing knowledge in a fun, modern way. It's a conference like no other. The programme has been released and is packed full of fantastic topics and speakers, both from the traditional world of academia and the new generation of social media enthusiasts, who specialise in disseminating, commenting and discussing major research. There are also over 30 pre-conference workshops on every topic imaginable.

(COI - I am luckily enough to be invited to speak at SMACC and receive financial support to attend)

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Critical Care Horizons

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. A call for papers has been issued, so if you have something interesting to say, and can say it in an engaging manner, please get in touch. The first issue will be released on January 1st 2015.

(COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.)

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Randomized Controlled Trials

Meta Analyses

Observational Studies

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Cochrane Reviews



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Guidelines & Position Statements

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Study Critiques

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Case Reports

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Clinical Review Articles













Non-Clinical Review Articles

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Basic Science Review Articles

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General Interest

World War 1

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I hope you find these links useful.

Until next week