This supplemental newsletter contains links to the important trials presented and simultaneously published today at the annual SCCM meeting in San Diego, including ANDROMEDA-SHOCK and POPPI, both discussed at #CCR19 last month. The videos of these presentations will be out in the next few weeks.
- Full Text: Hernández. Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock. The ANDROMEDA-SHOCK Randomized Clinical Trial. JAMA 2019;epublished February 17th
- Editorial: Angus. How Best to Resuscitate Patients With Septic Shock? JAMA 2019;epublished February 17th
- Full Text: Wade. Effect of a Nurse-Led Preventive Psychological Intervention on Symptoms of Posttraumatic Stress Disorder Among Critically Ill Patients. A Randomized Clinical Trial. JAMA 2019;epublished February 18th
- Editorial: Kross. Addressing the Psychological Symptoms of Critical IllnessThe Importance of “Negative” Trials in Guiding Next Steps. JAMA 2019;epublished February 18th
- Full Text: Beitler. Effect of Titrating Positive End-Expiratory Pressure (PEEP) With an Esophageal Pressure–Guided Strategy vs an Empirical High PEEP-Fio2 Strategy on Death and Days Free From Mechanical Ventilation Among Patients With Acute Respiratory Distress Syndrome. A Randomized Clinical Trial. JAMA 2019;epublished February 18th
- Editorial: Cavalcanti. The Elusive Search for “Best PEEP” and Whether Esophageal Pressure Monitoring Helps. JAMA 2019;epublished February 18th
- Full Text: Casey. Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults. N Engl J Med 2019;epublished February 18th
- Editorial: Kritek. Preventing Dogma from Driving Practice. N Engl J Med 2019;epublished February 18th
- Full Text: Arabi. Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis. N Engl J Med 2019;epublished February 18th
I hope you find this newsletter useful.
Newsletter 375 should be out later tonight or in the morning.