Newsletter 349 | August 19th 2018
Journal Watch | Newsletters | CCR Meeting 2019 | CCR18 Book | Podcast | Hot Articles | Topic of the Week | Reviews | Top 100 Studies | Guidelines | Journals
Welcome to the 349th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are a randomised controlled trial on dopamine for acute heart failure (ROPA-DOP); a systematic review and meta analysis on red cell transfusion thresholds in cardiac surgery; and observational studies on hypoxaemia in the ICU & the association of frailty with short-term outcomes, organ support and resource use. The latest SCCM guideline on pain, agitation/sedation, delirium, immobility, and sleep disruption was published this week, as were narrative reviews on difficult tracheal intubation, feeding intolerance & airway and ventilation management during CPR and after successful resuscitation.
Continuing our focus on the trials to be discussed at #CCR19, this week's Topic of the Week is, based on the PARAMEDIC2 trial, out-of-hospital cardiac arrest, starting with a paper on the role of adrenaline in cardiopulmonary resuscitation in tomorrow's Paper of the Day. Registration for the meeting is open, so don't miss out on the chance to discuss the best trials of 2018 with their chief investigators at the stunning Titanic, Belfast.
If you only have time to read one review article this week, then this should be top of your list - written by three of the most distinguished researchers in critical care, this paper on intravenous fluid therapy in critically ill adults is the definitive contemporary review on the subject.
In other news, registration for the final SMACC in Sydney opens in just a few hours. This will be the last opportunity to attend this unique conference which changed medical conferencing so much for the better.
Research
- Abstract: Sharma. Randomized Evaluation of Heart Failure With Preserved Ejection Fraction Patients With Acute Heart Failure and Dopamine: The ROPA-DOP Trial. JACC Heart Fail 2018;epublished August 7th
- Abstract: Morici. Management of cardiogenic shock in acute decompensated chronic heart failure: The ALTSHOCK phase II clinical trial. Am Heart J 2018;epublished July 20th
- Full Text: Lanspa. Echocardiogram-guided resuscitation versus early goal-directed therapy in the treatment of septic shock: a randomized, controlled, feasibility trial. J Intensive Care 2018;6:50
- Abstract: Chen. Cytokine Clearances in Critically Ill Patients on Continuous Renal Replacement Therapy. Blood Purif 2018;46(4):315-322
- Abstract: Kredentser. Preventing Posttraumatic Stress in ICU Survivors: A Single-Center Pilot Randomized Controlled Trial of ICU Diaries and Psychoeducation. Crit Care Med 2018;epublished August 16th
- Full Text: Nguyen. Intravenous ivabradine versus placebo in patients with low cardiac output syndrome treated by dobutamine after elective coronary artery bypass surgery: a phase 2 exploratory randomized controlled trial. Critical Care 2018;22:193
- Abstract: Thomalla. MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset. N Engl J Med 2018;379:611-622
- Abstract: Shehata. Restrictive compared with liberal red cell transfusion strategies in cardiac surgery: a meta-analysis. European Heart Journal 2018;ehy435
- Abstract: González-Castro. Meta-analysis of the effects of normal saline on mortality in intensive care. Rev Esp Anestesiol Reanim 2018;epublished August 9th
- Full Text: Yu. Clinical outcomes of prolonged infusion (extended infusion or continuous infusion) versus intermittent bolus of meropenem in severe infection: A meta-analysis. PLoS One 2018;13(7):e0201667
- Abstract: Zhang. Association of conflicts of interest with the results and conclusions of goal-directed hemodynamic therapy research: a systematic review with meta-analysis. Intensive Care Med 2018;epublished August 13th
- Full Text: Wirz. Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials. Critical Care 2018 22:191
- Full Text: Yazan. Balanced crystalloids versus isotonic saline in critically ill patients: systematic review and meta-analysis. J Intensive Care 2018;6:51
- Full Text: Gershengorn. Trends in Use of Daily Chest Radiographs Among US Adults Receiving Mechanical Ventilation. JAMA Network Open 2018;1(4):e181119
- Abstract: Hsu. Effect of Rosuvastatin on Acute Kidney Injury in Sepsis-Associated Acute Respiratory Distress Syndrome. Can J Kidney Health Dis 2018;5:2054358118789158
- Abstract: Jha. Intracranial Pressure Trajectories: A Novel Approach to Informing Severe Traumatic Brain Injury Phenotypes. Crit Care Med 2018;epublished August 16th
- Abstract: McCullough. The Statistical Curriculum Within Randomized Controlled Trials in Critical Illness. Crit Care Med 2018;epublished August 16th
- Abstract: Madsen. Association Between Traumatic Brain Injury and Risk of Suicide. JAMA 2018;320(6):580-588
- Abstract: Berg. End-tidal Carbon Dioxide During Pediatric In-Hospital Cardiopulmonary Resuscitation. Resuscitation 2018;epublished August 14th
- Full Text: Abe. Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries. Crit Care 2018;22(1):195
- Abstract: Roethlisberger. Impact of Aneurysm Multiplicity on Treatment and Outcome After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery 2018;epublished August 3rd
- Full Text: Ebner. Carbon dioxide dynamics in relation to neurological outcome in resuscitated out-of-hospital cardiac arrest patients: an exploratory Target Temperature Management Trial substudy. Critical Care 2018;22:196
- Full Text: Soussi. Hemodynamic management of critically ill burn patients: an international survey. Critical Care 2018;22:194
- Abstract: Mearelli. Derivation and Validation of a Biomarker-Based Clinical Algorithm to Rule Out Sepsis From Noninfectious Systemic Inflammatory Response Syndrome at Emergency Department Admission: A Multicenter Prospective Study. Crit Care Med 2018;46(9):1421-1429
- Abstract: Hutchings. Microcirculatory Impairment Is Associated With Multiple Organ Dysfunction Following Traumatic Hemorrhagic Shock: The MICROSHOCK Study. Crit Care Med 2018;46(9):e889–e896
- Abstract: McKown. Risk Factors for and Prediction of Hypoxemia during Tracheal Intubation of Critically Ill Adults. Ann Am Thorac Soc 2018;epublished August 15th
- Abstract: Lat. A multicenter, prospective, observational study to determine predictive factors for multidrug resistant pneumonia in critically ill adults: The DEFINE study. Pharmacotherapy 2018;epublished August 12th
- Full Text: SRLF Trial Group. Hypoxemia in the ICU: prevalence, treatment, and outcome. Ann Intensive Care 2018;8(1):82
- Abstract: Karvellas. Dynamic Prognostication in Critically Ill Cirrhotic Patients With Multiorgan Failure in ICUs in Europe and North America: A Multicenter Analysis. Crit Care Med 2018;epublished August 13th
- Abstract: Zampieri. Association of frailty with short-term outcomes, organ support and resource use in critically ill patients (ORCHESTRA Study). Intensive Care Med 2018;epublished August 13th
Guidelines
- Devlin. Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Crit Care Med 2018;46(9):e825-e873
- Devlin. Executive Summary: Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Crit Care Med 2018;46(9):1532-1548
- Devlin. Methodologic Innovation in Creating Clinical Practice Guidelines: Insights From the 2018 Society of Critical Care Medicine Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption Guideline Effort. Crit Care Med 2018;46(9):1457-1463
- Balas. Interpreting and Implementing the 2018 Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption Clinical Practice Guideline. Crit Care Med 2018;46(9):1464-1470
- Osuchowski. Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis. Infection 2018;epublished August 14th
- Postoperative pain management — 2018 consensus statement of the Section of Regional Anaesthesia and Pain Therapy of the Polish Society of Anaesthesiology and Intensive Therapy, the Polish Society of Regional Anaesthesia and Pain Therapy, the Polish Association for the Study of Pain and the National Consultant in Anaesthesiology and Intensive Therapy. Anaesthesiol Intensive Ther 2018;50(3):173–199
Review Articles
Airway
- Ahmed. Difficult tracheal intubation in critically ill. J Intensive Care 2018;6:49
- Lages. Ultrasound guided airway access. Rev Bras Anestesiol 2018;epublished August 17th
Neurological
- Tator. Metabolomics and Biomarker Discovery in Traumatic Brain Injury. J Neurotrauma 2018;35(16):831–1848
- Badhiwala. A Review of Clinical Trials in Spinal Cord Injury Including Biomarkers. J Neurotrauma 2018;35(16):1906–1917
- Cadotte. What Has Been Learned from Magnetic Resonance Imaging Examination of the Injured Human Spinal Cord: A Canadian Perspective. J Neurotrauma 2018;35(16):942–1957
Circulatory
- Finfer. Intravenous fluid therapy in critically ill adults. Nature Reviews Nephrology 2018;14:541–557
- Newell. Airway and ventilation management during cardiopulmonary resuscitation and after successful resuscitation. Critical Care 2018 22:190
- Donker . Left ventricular unloading during veno-arterial ECMO: a review of percutaneous and surgical unloading interventions. Perfusion 2018;epublished August 16th
- Bussard. Angiotensin II: a new therapeutic option for vasodilatory shock. Ther Clin Risk Manag 2018;14:1287–1298
Gastrointestinal
Nutrition
Renal
Endocrine
Haematological
Sepsis
- Heming. Immune Effects of Corticosteroids in Sepsis. Front Immunol 2018;9:1736
- Xu. Hotspot Analysis of Sepsis Literature. Med Sci Monit 2018;24:5427–5436
- Woźnica. Procalcitonin in liver dysfunction — Dr Jekyll or Mr Hyde? Anaesthesiol Intensive Ther 2018;50(3):226-229
Trauma
Immunology
Perioperative
- Echeverry-Marín. Anesthetic implications of muscular dystrophies. Colombian Journal of Anesthesiology 2018;46(3):228-239
- Mejía. Comprehensive patient-centered perioperative care: another step towards expanding horizons in anesthesiology. Colombian Journal of Anesthesiology 2018;46(3):240–245
- Lee. Does pediatric anesthesia cause brain damage? – Addressing parental and provider concerns in light of compelling animal studies and seemingly ambivalent human data. Korean J Anesthesiol 2018;71(4):255-273
- Kim. Cervical plexus block. Korean J Anesthesiol 2018;71(4):274-288
Miscellaneous
- Sousa. Burnout in anesthesiology. Rev Bras Anestesiol 2018;68(5):507-517
- Menezes. The role of end-of-life palliative sedation: medical and ethical aspects – review. Rev Bras Anestesiol 2018;epublished August 13th
Editorials
- Duggan. Improving communication, teamwork, and action during a "cannot intubate cannot oxygenate (CICO)" emergency: employing CICO as a cognitive aid mnemonic. Can J Anaesth 2018;epublished August 14th
- Tridente. Sepsis 3 and the burns patient: do we need Sepsis 3.1? Scars, Burns & Healing 2018;4:1–72018;4:1–7
- Nishibori. Histidine-rich glycoprotein as an excellent biomarker for sepsis and beyond. Critical Care 2018;22:209
Miscellaneous
- Honore. Adjuvant vitamin C in cardiac arrest patients undergoing renal replacement therapy: an appeal for a higher high-dose. Crit Care 2018;22(1):207
- Honore. Efficacy of polymyxin B hemoperfusion in and beyond septic shock: is an “endotoxin severity score” needed? Critical Care 2018;22:205
- Amaya-Zuñiga. Could ultrasound-guided internal jugular vein catheter insertion replace the use of chest X-ray? Critical Care 2018;22:206
- Koh. Practice Points in Performing Ultrasound-Guided Pleural Procedures. Chest 2018;154(2):461–462
- Tinti. Lung Fissures Detection With Transthoracic Ultrasound. Is It Simply a Matter of Artifacts? Chest 2018;154(2):453–455
- Dubey. Topicalisation of airway for awake fibre-optic intubation: Walking on thin ice. Indian J Anaesth 2018;62:625-7
- Jouffroy. Bundle of care taking into account time to improve long-term outcome after cardiac arrest. Critical Care 2018;22:192
- Martins. Uremic Frost in End-Stage Renal Disease. N Engl J Med 2018; 379:669
- Zante. ‘Chasing the dragon’ on the intensive care unit. Anaesthesiol Intensive Ther 2018;50(3):243
- Nguyen. Rapid Brain Death following Cardiac Arrest without Intracranial Pressure Rise and Cerebral Circulation Arrest. Case Rep Crit Care 2018;2018:2709174
- Gubbala. Severe adult-onset still's disease mimicking systemic infection. Indian J Crit Care Med 2018;22:616-8
- Mahto. Uncommon cause of acute liver failure with encephalopathy. Indian J Crit Care Med 2018;22:619-20
- Yadav. Unusual cause of hypotension in a polytrauma victim: A case of fahr's syndrome. Indian J Crit Care Med 2018;22:621-3
- Trivedi. Recurrent vertebrobasilar insufficiency—bow hunter’s syndrome. J Emerg Crit Care Med 2018;2:65
- Wang. A 63-Year-Old Man With Recurrent Dyspnea. Chest 2018;154(2):e55–e59
- DiBardino. A 67-Year-Old Woman With a “Shrunken” Left Lung and Recurrent Pneumonia. Chest 2018;154(2):e49–e53
- Suri. Spelunking Meckel Cave. A 31-Year-Old With Diplopia and Loss of Taste and Smell. Chest 2018;154(2):e45–e48
- Hassan. A Patient With Effusion Undergoing Pleural Biopsy. Chest 2018;154(2):e37–e39
- Alonso. A 48-Year-Old Woman Presenting With Syncope and Shortness of Breath. Chest 2018;154(2):e41–e43
Meetings
CCR19
Belfast, 18-19th January 2019
SMACC Sydney
Sydney, 26-29th March 2019
Women in ICM
London, February 6th
CCH Journal
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week
Rob
Supported by the Health Research Board
