Newsletter 348  |  August 12^th 2018

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The latest addition to the #CCR19 meeting programme

Welcome to the 348^th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on terlipressin versus noradrenaline for AKI in acute-on-chronic liver failure, restricted fluid bolus volume in early paediatric septic shock & early CPAP in acute respiratory failure in children with impaired immunity; systematic reviews and meta analyses on complications and failures of central vascular access devices & laryngeal injury and upper airway symptoms after intubation during critical care; and guidelines and position statements on steroid therapy for sepsis, disorders of consciousness & spinal motion restriction in trauma. In addition, there are also excellent narrative reviews on cerebral edema in traumatic brain injury, immunoadjuvant therapy in sepsis &  prehospital ultrasonography. 

This week's Topic of the Week is space medicine, starting with a paper on anaesthesia in space in tomorrow's Paper of the Day. If you only have time to read one review article this week, try this one on guideline- and pathophysiology-based protocols for neurocritical care.

Prof Jason Sperry (Pittsburgh) is the latest speaker to be added to the Critical Care Reviews Meeting 2019, where he will discuss the very recently published PAMPer trial, reporting a lage mortality benefit from the use of plasma in trauma by prehospital air medical teams. If you haven't registered yet for the expanded two day meeting, where chief investigators for the best critical care trials of 2018 come to Titanic, Belfast, to discuss their work, then don't wait too long or you might miss out!

Research

+ - Randomised Controlled Trials Click to collapse

• Abstract:  Arora. Terlipressin is superior to noradrenaline in the management of acute kidney injury in acute on chronic liver failure. Hepatology 2018;epublished August 3rd
• Abstract:  Rickard. Dressings and securements for the prevention of peripheral intravenous catheter failure in adults (SAVE): a pragmatic, randomised controlled, superiority trial. Lancet 2018;392
• Full Text:  Inwald. Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial. Arch Dis Child 2018;epublished August 7th
• Abstract:  Mahmoodpoor. Effect of a Probiotic Preparation on Ventilator-Associated Pneumonia in Critically Ill Patients Admitted to the Intensive Care Unit: A Prospective Double-Blind Randomized Controlled Trial. Nutr Clin Pract 2018;epublished August 8th
• Full Text:  Sieber. Effect of Depth of Sedation in Older Patients Undergoing Hip Fracture Repair on Postoperative Delirium: The STRIDE Randomized Clinical Trial. JAMA Surg 2018;epublished August 8th
• Abstract:  Peters. Randomized Study of Early Continuous Positive Airways Pressure in Acute Respiratory Failure in Children With Impaired Immunity (SCARF) ISRCTN82853500. Pediatr Crit Care Med 2018;epublished August 7th
• Full Text:  Momenfar. Studying the effect of abdominal massage on the gastric residual volume in patients hospitalized in intensive care units. Journal of Intensive Care 2018;6:47

+ - Systematic Reviews & Meta Analyses Click to collapse

• Abstract:  Brodsky. Laryngeal Injury and Upper Airway Symptoms After Oral Endotracheal Intubation With Mechanical Ventilation During Critical Care: A Systematic Review. Crit Care Med 2018;epublished August 9th
• Abstract:  Takashima. Complication and Failures of Central Vascular Access Device in Adult Critical Care Settings. Crit Care Med 2018;epublished August 7th
• Abstract:  Zhong. Quality of critical care clinical practice guidelines: Assessment with AGREE II instrument. J Clin Anesthesia 2018;51:40-47
• Full Text:  Aubron. Platelet storage duration and its clinical and transfusion outcomes: a systematic review. Critical Care 2018;22:185
• Full Text:  Sanfilippo. Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis. Critical Care 2018;22:183

+ - Observational Studies Click to collapse

• Abstract:  Dowell. Epidemiology of Cause of Death in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med 2018;epublished August 7th
• Abstract:  Mentzelopoulos. Exposure to Stress-Dose Steroids and Lethal Septic Shock After In-Hospital Cardiac Arrest: Individual Patient Data Reanalysis of Two Prior Randomized Clinical Trials that Evaluated the Vasopressin-Steroids-Epinephrine Combination Versus Epinephrine Alone. Cardiovasc Drugs Ther 2018;epublished August 7th

+ - Cochrane Reviews Click to collapse

• Darwood. Surgery versus thrombolysis for initial management of acute limb ischaemia. Cochrane Database of Systematic Reviews 2018;Issue 8. Art. No.: CD002784

+ - Protocols Click to collapse

• Casey. Manual ventilation to prevent hypoxaemia during endotracheal intubation of critically ill adults: protocol and statistical analysis plan for a multicentre randomised trial. BMJ Open 2018;8:e022139

Guidelines

• Lamontagne. Corticosteroid therapy for sepsis: a clinical practice guideline. BMJ 2018;362:k3284
• Acute Cardiovascular Care Association Position Paper on Intensive Cardiovascular Care Units: An update on their definition, structure, organisation and function. Eur Heart J Acute Cardiovasc Care 2018;7(1):80-95
• Comprehensive systematic review update summary: Disorders of consciousness. Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology; the American Congress of Rehabilitation Medicine; and the National Institute on Disability, Independent Living, and Rehabilitation Research. Neurology 2018;epublished August 8th
  
  • Commentary:  Fins. Ethical, palliative, and policy considerations in disorders of consciousness. Neurology 2018;epublished August 8th
  • Recommendation Summary:  Practice guideline update recommendations summary: Disorders of consciousness. Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology; the American Congress of Rehabilitation Medicine; and the National Institute on Disability, Independent Living, and Rehabilitation Research. Neurology 2018;epublished August 8th
• Fischer. Spinal Motion Restriction in the Trauma Patient – A Joint Position Statement. Prehospital Emergency Care 2018;epublished August 9th

Review Articles

+ - Clinical Click to collapse

Neurological

• Norisue. Preliminary guideline- and pathophysiology-based protocols for neurocritical care. Journal of Intensive Care 2018;6:45
• Jha. Pathophysiology and treatment of cerebral edema in traumatic brain injury. Neuropharmacology 2018;epublished August 4th
• Souza. Multiprofessional care for delirium patients in intensive care: integrative review. Rev Gaucha Enferm. 2018;39:e20170157
• Evered. Postoperative Cognitive Dysfunction and Noncardiac Surgery. Anesthesia & Analgesia 2018;127(2):496-505
• El-Boghdadly. Local anesthetic systemic toxicity: current perspectives. Local and Regional Anesthesia 2018;11:35—44

Circulatory

• Arabi. The role of interventional radiology in the management of hemodynamically compromised patients. Intensive Care Med 2018;44(8):1334–1338
• Tschöpe. Mechanical Unloading by Fulminant Myocarditis: LV-IMPELLA, ECMELLA, BI-PELLA, and PROPELLA Concepts. Journal of Cardiovascular Translational Research 2018;epublished August 6th
• Coetzee. Myocardial injury after non-cardiac surgery: Time to shed the ignorance. S Afr Med J 2018;108(6):464-467
• Fujita. Myocardial tissue engineering strategies for heart repair: current state of the art. Interactive CardioVascular and Thoracic Surgery 2018;ivy208
• Stephen. Venous thoracic outlet syndrome: A short review. Indian J Vasc Endovasc Surg 2018;5:168-73
• Squiers. Coronary artery bypass grafting—fifty years of quality initiatives since Favaloro. Ann Cardiothorac Surg 2018;7(4):516-520
• Park. Percutaneous coronary intervention in left main disease: SYNTAX, PRECOMBAT, EXCEL and NOBLE—combined cardiology and cardiac surgery perspective. Ann Cardiothorac Surg 2018;7(4):521-526
• Kayatta. Hybrid coronary revascularization for the treatment of multivessel coronary artery disease. Ann Cardiothorac Surg 2018;7(4):500-505
• Huang. Engineered circulatory scaffolds for building cardiac tissue. J Thorac Dis 2018;10(Suppl 20):S2312-S2328
• Geng. Interfacial tissue engineering of heart regenerative medicine based on soft cell-porous scaffolds. J Thorac Dis 2018;10(Suppl 20):S2333-S2345
• Di Franco.. Biomaterials and heart recovery: cardiac repair, regeneration and healing in the MCS era: a state of the “heart”. J Thorac Dis 2018;10(Suppl 20):S2346-S2362
• Perrucci. Cardiac fibrosis in regenerative medicine: destroy to rebuild. J Thorac Dis 2018;10(Suppl 20):S2376-S2389
• Iop. Bioengineered tissue solutions for repair, correction and reconstruction in cardiovascular surgery. J Thorac Dis 2018;10(Suppl 20):S2390-S2411
• Grimaldi. Potential clinical benefits of cell therapy in coronary heart disease: an update. J Thorac Dis 2018;10(Suppl 20):S2412-S2422

Respiratory

• Vetrugno. An easier and safe affair, pleural drainage with ultrasound in critical patient: a technical note. Critical Ultrasound Journal 2018;10:18
• Neethling. Point-of-care and lung ultrasound incorporated in daily practice. S Afr Med J 2018;108(5):376-381
• Petrella. Artificial lung. J Thorac Dis 2018;10(Suppl 20):S2329-S2332
• Rosso. Lung transplantation, ex-vivo reconditioning and regeneration: state of the art and perspectives. J Thorac Dis 2018;10(Suppl 20):S2423-S2430

Hepatobiliary

•  Samuel. Management of patients with liver diseases on the waiting list for transplantation: a major impact to the success of liver transplantation. BMC Med 2018;16:113

Renal

• Roberts. Clinical Pharmacokinetics in Kidney Disease: Application to Rational Design of Dosing Regimens. CJASN 2018;13(8):1254-1263

Endocrine

• du Toit. A practical approach to managing diabetes in the perioperative period. S A fr Med J 2018;108(5):369-375

Haematological

• Alli. Inherited bleeding disorders. S Afr Med J 2018;108(1):9-15
• Alli. Acquired bleeding disorders. S Afr Med J 2018;108(3):159-165

Sepsis

• Watanabe. Immunoadjuvant therapy in sepsis: novel strategies for immunosuppressive sepsis coming down the pike. Acute Medicine & Surgery 2018;epublished August 6th

Trauma

• Ketelaars. ABCDE of prehospital ultrasonography: a narrative review. Critical Ultrasound Journal 2018;10:17

Toxicology

• Ward. Opioid Use Disorders: Perioperative Management of a Special Population. Anesthesia & Analgesia 2018;127(2):539-547

Miscellaneous

• Panesar. Surgery in space. BJS 2018;105:1234–1243
• Ghidini. Regenerative medicine and 3D bioprinting for human space exploration and planet colonisation. J Thorac Dis 2018;10(Suppl 20):S2363-S2375

+ - Non-Clinical Click to collapse

• Zhang. Decision curve analysis: a technical note. Ann Transl Med 2018;6(15):308
• Schober. Repeated Measures Designs and Analysis of Longitudinal Data: If at First You Do Not Succeed—Try, Try Again. Anesthesia & Analgesia 2018;127(2):569–575

Commentaries

• Glazier. Organ Donation and the Principles of Gift Law. CJASN 2018;13(8):1283-1284
• Rubin. Addressing Barriers to Inclusion of Pregnant Women in Clinical Trials. JAMA 2018;epublished August 8th
• Shekelle. Clinical Practice GuidelinesWhat’s Next? JAMA 2018;epublished August 9th
• Platt. Data Enclaves for Sharing Information Derived From Clinical and Administrative Data. JAMA 2018;epublished August 6th

Correspondence

• Pani. Persistence of cortical neuronal activity in the dying brain. Resuscitation 2018;130:e5–e7

Case Reports

• Elkbuli. Survival from Clostridium toxic shock syndrome: Case report and review of the literature. Int J Surg Case Rep 2018;50:64-67

Meetings

CCR19

Belfast, 18-19th January 2019

SMACC Sydney

Sydney, 26-29th March 2019

Women in ICM

London, February 6th

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week

Rob

Supported by the Health Research Board