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CCR-Newsletter-BannerNewsletter 340  |  June 17th 2018

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CCR19 170618

Latest Addition to the Programme - the EOLIA trial


Welcome to the 340th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are the BICAR-ICU randomised controlled trial, investigating sodium bicarbonate for metabolic acidaemia; observational studies on subphenotypes in septic shock & late mortality after acute hypoxic respiratory failure; guidelines on cancer patients requiring intensive care support & intermediate care units; narrative reviews on perioperative myocardial injury and the contribution of hypotension, vasoactive agents in shock & ventilation during extracorporeal support. There are also contrasting editorials on whether trials that report a neutral or negative treatment effect improve the care of critically ill patients - Yes & No; thrombocytopenia in the ICU & sepsis: who will shoot first? pharma or diagnostics; as well as commentaries on severe pulmonary embolism, type 2 myocardial infarction & acute kidney injury.

With the publication of the BICAR-ICU trial, this week's Topic of the Week is bicarbonate therapy, starting with a paper on sodium bicarbonate in the treatment of acidosis in sepsis in tomorrow's Paper of the Day.

Turning to the Critical Care Reviews Meeting 2019, I'm delighted to announce the addition of the EOLIA trial, investigating ECMO for severe ARDS. This will be presented and discussed by Prof Niall Ferguson from Toronto, one of the authors of the published trial.

Based on this, if you only have time to read one review article this week, try this one on indications for extracorporeal support: why do we need the results of the EOLIA trial?



Review Articles












Belfast, 18-19th January 2019

SMACC 2019

SMACC Sydney

Sydney, 26-29th March 2019


Women in ICM

London, February 6th

CCH Journal

Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive.  If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.

COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.

I hope you find these links useful.

Until next week


Supported by the Health Research Board

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