#BMBTL17 Resuscitation Conference | October 16th 2017 | Montreal
Welcome to the 292nd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. There are loads of great papers to read this week, including a randomised controlled trial on spironolactone in acute heart failure, a French guideline on targeted temperature management in the ICU, plus reviews on brain multimodality monitoring, ECMO, and adjunctive therapies in septic shock by Gram negative MDR/XDR infections. If you only have time to read one review this week, try this paper on the future of mechanical ventilation
- Abstract: Butler. Efficacy and Safety of Spironolactone in Acute Heart Failure: The ATHENA-HF Randomized Clinical Trial. JAMA Cardiol 2017;epublished July 12th
- Full Text: Clark. Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children. PLoS One 2017;12(7):e0180280
- Full Text: Anantasit. Ultrasound Versus Traditional Palpation to Guide Radial Artery Cannulation in Critically Ill Children: A Randomized Trial. J Ultrasound Med 2017;epublished July 8th
- Full Text: Belenguer-Muncharaz. Non-Invasive Mechanical Ventilation Versus Continuous Positive Airway Pressure Relating to Cardiogenic Pulmonary Edema in an Intensive Care Unit. Arch Bronconeumol 2017;epublished July 6th
- Abstract: Verbeek. Intra-operative protective mechanical ventilation in lung transplantation: a randomised, controlled trial. Anaesthesia 2017;72(8):993-1004
- Full Text: Busse. Clinical Experience With IV Angiotensin II Administration: A Systematic Review of Safety. Crit Care Med 2017;45(8):1285-1294
- Abstract: de Waha. Multivessel versus culprit lesion only percutaneous coronary intervention in cardiogenic shock complicating acute myocardial infarction: A systematic review and meta-analysis. Eur Heart J Acute Cardiovasc Care 2017;epublished July 1st
- Full Text: Serafim. Outcomes of subsyndromal delirium in ICU: a systematic review and meta-analysis. Critical Care 2017;21:179
- Full Text: Zhao. High-flow nasal cannula oxygen therapy is superior to conventional oxygen therapy but not to noninvasive mechanical ventilation on intubation rate: a systematic review and meta-analysis. Critical Care 2017;21:184
- Abstract: Thiele. Percutaneous short-term active mechanical support devices in cardiogenic shock: a systematic review and collaborative meta-analysis of randomized trials. Eur Heart J 2017;epublished July 7th
- Full Text: Alshamsi. Postpyloric feeding in critically ill patients: Updated systematic review, meta-analysis and trial sequential analysis of randomized trials. Saudi Critical Care Journal 2017;1(1):6-23
- Abstract: Zhao. External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome. Intensive Care Med 2017;43(8):1123–1131
- Full Text: Emerson. Geographical access to critical care services in Scotland. JICS 2017;epublished July 13th
- Full Text: Waldauf. Factors associated with success in the oral part of the European Diploma in Intensive Care. JICS 2017;epublished July 5th
- Full Text: Iizuka. Low-dose immunoglobulin G is not associated with mortality in patients with sepsis and septic shock. Critical Care 2017;21:181
- Full Text: Trupka. Enhanced antimicrobial de-escalation for pneumonia in mechanically ventilated patients: a cross-over study. Critical Care 2017;21:180
- Full Text: Hu. Severity of acute gastrointestinal injury grade is a predictor of all-cause mortality in critically ill patients: a multicenter, prospective, observational study. Critical Care 2017;21:188
- Abstract: Ji. Post-admission outcomes of participants in the PARAMEDIC trial: a cluster randomised trial of mechanical or manual chest compressions. Resuscitation 2017;epublished July 5th
- Abstract: Moseby-Knappe. Head computed tomography for prognostication of poor outcome in comatose patients after cardiac arrest and targeted temperature management. Resuscitation 2017;epublished July 4th
- Full Text: Giacobbe. Combined use of serum (1,3)-β-d-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units. Critical Care 2017;21:176
- Full Text: Rajajee. Protocol based invasive intracranial pressure monitoring in acute liver failure: feasibility, safety and impact on management. Critical Care 2017;21:178
- Abstract: Roger. Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. Int J Antimicrob Agents 2017;epublished July 6th
- Osadnik. Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2017, Issue 7. Art. No.: CD004104
- Norman. Antiseptics for burns. Cochrane Database of Systematic Reviews 2017, Issue 7. Art. No.: CD011821
- Desborough. Desmopressin use for minimising perioperative blood transfusion. Cochrane Database of Systematic Reviews 2017, Issue 7. Art. No.: CD001884
- Pagel. The impact of phosphate-balanced crystalloid infusion on acid-base homeostasis (PALANCE study): study protocol for a randomized controlled trial. Trials 2017;18(1):313
- Zhou. The predictive value of serial changes in diaphragm function during the spontaneous breathing trial for weaning outcome: a study protocol BMJ Open 2017;7:e015043
- Rol. The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients. BMJ Open 2017;7:e015734
- Muengtaweepongsa. Targeted temperature management in neurological intensive care unit. World J Methodol 2017;(2):55-67
- Tasneem. Brain Multimodality Monitoring: A New Tool in Neurocritical Care of Comatose Patients. Critical Care Research and Practice 2017;2017:6097265
- Tobar. Cognitive stimulation and occupational therapy for delirium prevention. Rev Bras Ter Intensiva 2017;29(2):248–252
- Baran. Extracorporeal Membrane Oxygenation (ECMO) and the Critical Cardiac Patient. Curr Transpl Rep 2017;epublished July 10th
- Tafner. Recent advances in bedside microcirculation assessment in critically ill patients. Rev Bras Ter Intensiva 2017;29(2):238–247
- Barcan. Monitoring Acute Myocardial Infarction Complicated with Cardiogenic Shock — from the Emergency Room to Coronary Care Units. Journal of Cardiovascular Emergencies 2017;3(2):61-71
- Muser. Management of ventricular tachycardia storm in patients with structural heart disease. World J Cardiol 2017;9(6):521-530
- Gattinoni. The future of mechanical ventilation: lessons from the present and the past. Critical Care 2017;21:183
- Bugedo. Does the use of high PEEP levels prevent ventilator-induced lung injury? Rev Bras Ter Intensiva 2017;29(2):231–237
- Sadikot. Nanomedicine for Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome. Biomed Hub 2017;2:477086
- Pagnamenta. Invasive haemodynamic evaluation of the pulmonary circulation in pulmonary hypertension. Swiss Med Wkly 2017;147:w14445
- Oliveira. Safe prone checklist: construction and implementation of a tool for performing the prone maneuver. Rev Bras Ter Intensiva 2017;29(2):131–141
- Johnson. High-flow oxygen therapy in hypoxemic respiratory failure: Review. Saudi Critical Care Journal 2017;1(1):43-46
- Kosałka. Disorders of nutritional status in sepsis – facts and myths. Prz Gastroenterol 2017;12(2):73–82
- Gudnason. Secondary sclerosing cholangitis in critically ill patients: current perspectives. Clin Exp Gastroenterol 2017;10:105-111
- Shimizu. History and current status of polymyxin B-immobilized fiber column for treatment of severe sepsis and septic shock. Ann Gastroenterol Surg 2017;00:1–9
- Rodrigo-Troyano. The respiratory threat posed by multiresistant Gram-negative bacteria. Respirology 2017;epublished July 6th
- Aston. Pneumonia in the developing world: Characteristic features and approach to management. Respirology 2017;epublished July 6th
- Hui. A clinical approach to the threat of emerging influenza viruses in the Asia-Pacific region. Respirology 2017;epublished July 6th
- Garg. Resurgence of Polymyxin B for MDR/XDR Gram-Negative Infections: An Overview of Current Evidence. Critical Care Research and Practice 2017;2017:3635609
- Busani. The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDR/XDR Infections. Canadian Journal of Infectious Diseases and Medical Microbiology 2017;2808203
- Gonzaleza. Antifungal pharmacodynamics: Latin America's perspective. Braz J Infect Dis 2017;21(1):79–87
- Honickel. The Reversal of Direct Oral Anticoagulants in Animal Models. Shock 2017;48(2):144-158
- Finch. The past decade in bench research into pulmonary infectious diseases: What do clinicians need to know?. Respirology 2017;22:1062–1072
- Gazzin. The molecular basis of jaundice: An old symptom revisited. Liver Int 2017;37:1094–1102
- Cariou. Targeted temperature management in the ICU: guidelines from a French expert panel. Anaesth Crit Care Pain Med 2017;epublished July 5th
- The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections. World J Emerg Surg 2017;12:29
- Baigent. Challenges in conducting clinical trials in nephrology: conclusions from a Kidney Disease—Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International 2017;92(2):297-305
- Maury. Intensive Care Medicine in 2050: the future of medical imaging. Intensive Care Med 2017;43(8):1135–1137
- Kalil. Is Early Goal-Directed Therapy Harmful to Patients With Sepsis and High Disease Severity? Crit Care Med 2017;45(8):1265-1267
- Mandourah. Saudi critical care society. A decade; but it is just the beginning! Saudi Critical Care Journal 2017;1(1):1-5
- Tanemoto. Calculated Bicarbonate for Acid-Base Disorders. The American Journal of Medicine 2017;epublished July 4th
- D'Empaire. What every intensivist should know about handovers in the intensive care unit. Rev Bras Ter Intensiva 2017;29(2):121–123
- Bakker. Lactate is THE target for early resuscitation in sepsis. Rev Bras Ter Intensiva 2017;29(2):124–127
- de Lange. Small steps beyond benchmarking. Rev Bras Ter Intensiva 2017;29(2):128–130
- Elwyn. Can Patients Make Recordings of Medical Encounters? What Does the Law Say? JAMA 2017;epublished July 10th
- Pati. Cellular therapies in trauma and critical care medicine: Looking towards the future. PLoS Med 2017;14(7):e1002343
- Trummer. Controlled automated reperfusion of the whole body after 120 minutes of Cardiopulmonary resuscitation: first clinical report. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2017;25:66
- Jackson. Consideration of underlying causes of pneumothoraces in patients presenting with their first pneumothorax. JICS 2017;epublished July 10th
- Shacklock. Neurological effects of fat embolism syndrome: A case report. JICS 2017;epublished July 10th
It's now just 6 months until the Critical Care Reviews Meeting 2018, where the chief investigators for the best critical care trials of 2017 come to discuss their work and try to answer the question clinicians want to know - should I change my practice based on this trial? From Brisbane, Australia, Prof Bala Ventakesh will explore the ADRENAL trial, examining hydrocortisone in septic shock in the biggest sepsis trial ever undertaken. Split between Dublin and Melbourne, Prof Alistair Nichol will explain the findings of the TRANSFUSE trial, comparing transfusion of the freshest available blood with standard issued red cells. From Nantes, France, Dr Jean-Baptiste Lascarrou will consider the findings of the MACMAN trial, evaluating video laryngoscopy in the ICU. Dr Ashish Khanna, from the Cleveland Clinic, USA, will reflect on ATHOS-3, the first large clinical trial examining angiotensin II in septic shock. We also have Prof Andrew Rhodes, from London, exploring the latest iteration of the Surviving Sepsis Campaign, published earlier this year. There are still additional speakers to add to the programme, so the meeting will continue to grow and get better and better.
We sold out #CCR17 and had to turn people away. At present we are way up on registrations compared to the same time-point in 2016. So, if you intend on coming, don't leave it too late to register. There is plenty of space still at present, but I expect the meeting will sell out well before it's date of Friday January 19th. Don't worry if you can't make it, as the talks will be recorded and put online for free viewing as usual. However, there is nothing like being there in person and having the opportunity to chat with these chief investigators. Numbers are strictly limited to ensure this remains a small, intimate meeting. It would be a shame to miss out......
The ANZICS/ACCCN Annual Scientific Meeting, which incorporates the annual Paediatric and Neonatal Intensive Care Conference, will be held at the Gold Coast Convention and Exhibition Centre, 11-13 October 2017. The Annual Scientific Meeting will be the preeminent critical care conference in Australasia for the calendar year and will be an important platform that will allow doctors, nurses and allied health practitioners to meaningfully connect and discuss new developments and research in the field of intensive and critical care.
The theme of the Meeting is “Thinking Outside the Flags” and will focus upon innovative and challenging advances that lie outside the safe zone of current practice, as well as the potential dangers that they may bring. A number of highly regarded international speakers will join our distinguished national and local speakers, experts in the field of intensive care medicine, nursing and allied health, promising delegates an exciting and challenging program.
Registration and the call for abstracts will open on 20 March 2017. For further information or to express your interest in attending, please visit http://intensivecareasm2017.com.au/.
#BMBTL17 is a conference on resuscitation that focuses on the skills and knowledge needed to bring your critically ill patients…back to life !
With cutting edge topics and a world class faculty, the conferences will be packed with clinical pearls and only the stuff that matters !
Ventilation, airway, EKGs, pediatric pearls, ultrasound and so much more…don’t miss this amazing conference ! It will be held on October 16th 2017 in downtown Montreal.
FemInEM.org is excited to bring you our first ever, in person conference, FIX2017! The FemInEM Idea Exchange is all about education, inspiration and motivation. Our world renowned faculty will speak from their hearts and minds, providing the substance and spark for you to change the world. We will meet, greet and motivate each other, pushing the limits of our previous selves. You won't want to miss it - October 4th to 6th, NYC.
State-of-the-Art is back, for the 3rd year of its new format and an all-new venue in Liverpool for 2017. The futurism and innovation theme continues with novel topics including robotics, optical imaging of bacterial infection, new technology in patient recovery, and new device interventions in acute cardiology.
However, the focus on day-to-day care is not lost, and there are clinical updates in acute medicine, ARDS, mechanical ventilation, trauma, nutrition, rehabilitation, endocrine management in ICU, cancer patients in ICU, the difficult and altered airway, and much more. Pragmatic "how I treat..." sessions proved popular last year and will continue, along with meaningful debates on UK critical care, including the trend toward centralisation.
In addition, the trademark vibe of SOA will still be there with pop-up talks, panel debates, 'meet the expert' booths, new generation video e-posters, parent and infant facilities, two drinks evenings, and a new final night after-party. Registration and abstract submission is now open at http://soa.ics.ac.uk.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week
Supported by the Health Research Board