March 12th 2012
Welcome to the 14th Critical Care Reviews Newsletter. Every week over two hundred clinical and scientific journals are monitored and the most important and interesting research publications in critical care are highlighted. These studies are added to the Journal Watch section of the website on a daily basis, as publication occurs. A link to either the full text or abstract, depending on the publishers degree of open access, is attached.
As there has been very little prospective research of clinical significance published in the past week, I've decided to open the Newsletter to newly published open acess review articles, guidelines and other relevant publications. These will be added to their relevant webpages also.
Scandanavian Journal of Trauma, Resuscitation and Emergency Medicine
- Gillman. Point of care ultrasound: the visual stethoscope of the 21st century. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012;20:18
Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science
- Toner. Is H5N1 Really Highly Lethal? Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science 2012; epublished ahead of print
- Marik. Immunonutrition in the surgical patient. Marik. Immunonutrition in the surgical patient. Minerva Anestesiologica 2012;78(3):336-42
- Cortés. Acute respiratory distress syndrome: evaluation and management. Minerva Anestesiologica 2012;78(3);343-57
- Colomina. Perioperative use of prothrombin complex concentrates. Minerva Anestesiologica 2012;78(3):358-68
- McGrane. Sedation in the Intensive Care Unit. Minerva Anestesiologica 2012;78(3):369-80
Journal of Anesthesia
Journal of Anaesthesiology Clinical Pharmacology
- Grover. Perioperative vision loss: A complication to watch out. J Anaesthesiol Clin Pharmacol 2012;28:11-6
Annals of Cardiac Anaesthesia
- Chauhan S, Subin S. Extracorporeal membrane oxygenation, an anesthesiologist's perspective: Physiology and principles. Part 1. Ann Card Anaesth 2011;14:218-29
- Chauhan. Extracorporeal membrane oxygenation - An anesthesiologist's perspective - Part II: Clinical and technical consideration. Ann Card Anaesth 2012;15:69-82
Annals of Intensive Care
Journal of the Intensive Care Society
- van Harten. A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia. Anaesthesia 2012;67(3):280-293
Critical Care: Percutaneous Tracheostomy
To evaluate the feasibility of ultrasound-guided percutaneous tracheostomy in obese critically ill patients, Guinot and colleagues compared this procedure in 26 obese subjects with 24 non-obese subjects (BMI 35 v 25 kg/m2, p<0.001). There were no differences in procedure duration (9 min v 10 min; p=0.1) or complication rate (35% v 33%; p=0.92), with most complications being of minor significance, including hypotension, desaturation, tracheal cuff puncture and minor bleeding. No surgical conversions were required in either group and no deaths occurred.
The Lancet: Stem Cell Therapy for Ischaemic Cardiac Dysfunction
In the prospective CADUCEUS study, Makker and colleagues randomised 25 patients with left ventricular ejection fraction of 25—45% 2—4 weeks after myocardial infarction to receive either autologous cardiosphere stem cells or standard care in a 2:1 ratio. At 6 months, therapy with cardiosphere stem cells was associated with reductions in scar mass (p=0·001), increases in viable heart mass (p=0·01), regional contractility (p=0·02), and regional systolic wall thickening (p=0·015), when assessed with MRI . However, there were no differences in end-diastolic volume, end-systolic volume, or left ventricular ejection fraction. The authors conclude intracoronary infusion of cardiosphere stem cells after myocardial infarction is safe and should progress to phase 2 studies.
- Difficult Airway Society Extubation Guidelines Group. Difficult Airway Society Guidelines for the management of tracheal extubation. Anaesthesia 2012;67(3):318-340
- Editorial: Heidegger. Extubation of the difficult airway – an important but neglected topic. Anaesthesia 2012;67(3):213-215
I hope you find the Newsletter useful.
Until next week