Welcome to the 267th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. After a year of preparation, the Critical Care Reviews Meeting 2017 is finally here. If you are planning on coming, but haven't yet booked, you should do so now. The event is over 90% sold and the final rush for registration has started, so don't delay any longer.
The highlight of this week's newsletter is the latest edition of the Surviving Sepsis Campaign Guideline. With two authors from this team on faculty at #CCR17, there is guaranteed to be some insightful discussion.
This week's Topic of the Week is the Critical Care Reviews Meeting 2017, starting with a critique of fluid bolus resuscitation in severe sepsis in tomorrow's Paper of the Day.
See you in Titanic on Friday.
- Abstract: Ahn. Transoesophageal echocardiographic evaluation of central venous catheter positioning using Peres’ formula or a radiological landmark-based approach: a prospective randomized single-centre study. Br J Anaesth 2017;118(2):215-222
- Abstract: Humphreys. Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) in children: a randomized controlled trial. Br J Anaesth 2017;118(2):232-238
- Abstract: Drake-Brockman. The effect of endotracheal tubes versus laryngeal mask airways on perioperative respiratory adverse events in infants: a randomised controlled trial. Lancet 2017;epublished January 17th
- Abstract: Baete. The Effect of Deep Versus Moderate Neuromuscular Block on Surgical Conditions and Postoperative Respiratory Function in Bariatric Laparoscopic Surgery: A Randomized, Double Blind Clinical Trial. Anesth Analg 2017;epublished January 19th
- Abstract: Yelnik. AMOBES (Active Mobility Very Early After Stroke): A Randomized Controlled Trial. Stroke. 2016;epublished December 22nd
- Full Text: Mayr. Proportion and Cost of Unplanned 30-Day Readmissions After Sepsis Compared With Other Medical Conditions. JAMA epublished January 22nd
- Full Text: Davis. Association of Delirium With Cognitive Decline in Late LifeA Neuropathologic Study of 3 Population-Based Cohort Studies. JAMA Psychiatry 2017;epublished January 18th
- Full Text: Ahn. Financial ties of principal investigators and randomized controlled trial outcomes: cross sectional study. BMJ 2017;356:i6770
- Full Text: Compher. Greater Protein and Energy Intake May Be Associated With Improved Mortality in Higher Risk Critically Ill Patients: A Multicenter, Multinational Observational Study. Crit Care Med 2017;45(2):156–163
- Full Text: von Bahr. Long-Term Survival in Adults Treated With Extracorporeal Membrane Oxygenation for Respiratory Failure and Sepsis. Crit Care Med 2017;45(2):164–170
- Full Text: Helmerhorst. Metrics of Arterial Hyperoxia and Associated Outcomes in Critical Care. Crit Care Med 2017;45(2):187–195
- Abstract: Ivie. Patient Eligibility for Randomized Controlled Trials in Critical Care Medicine: An International Two-Center Observational Study. Crit Care Med 2017;45(2):216–224
- Full Text: Santamaria. Readmissions to Intensive Care: A Prospective Multicenter Study in Australia and New Zealand. Crit Care Med 2017;45(2):290–297
- Abstract: van Vught. The Host Response in Sepsis Patients Developing Intensive Care Unit-acquired Secondary Infections. Am J Respir Crit Care Med 2017;epublished January 19th
- Abstract: Franchineau. Bedside Contribution of Electrical Impedance Tomography to Set Positive End-Expiratory Pressure for ECMO-Treated Severe ARDS Patients. Am J Respir Crit Care Med 2017;epublished January 19th
- Full Text: Peng. Does training improve diagnostic accuracy and inter-rater agreement in applying the Berlin radiographic definition of acute respiratory distress syndrome? A multicenter prospective study. Critical Care 2017;21:12
- Abstract: Jolley. Point Prevalence Study of Mobilization Practices for Acute Respiratory Failure Patients in the United States. Crit Care Med 2017;45(2):205–215
- Tsujimoto. Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy (Protocol). Cochrane Database of Systematic Reviews 2016, Issue 12. Art. No.: CD012467
- Andriolo. Effectiveness and safety of procalcitonin evaluation for reducing mortality in adults with sepsis, severe sepsis or septic shock. Cochrane Database of Systematic Reviews 2017, Issue 1. Art. No.: CD010959
- Mishra. Enhanced recovery after surgery: Neuroanaesthetic perspective. J Neuroanaesthesiol Crit Care 2017;4:17-22
- Monteiro. 'ROSE concept' of fluid management: Relevance in neuroanaesthesia and neurocritical care. J Neuroanaesthesiol Crit Care 2017;4:10-6
- Belliato. Automated weaning from mechanical ventilation. World J Respirol 2016;6(2):49-53
- Trovato. Thoracic ultrasound: A complementary diagnostic tool in cardiology. World J Cardiol 2016;8(10):566-574
- Nguyen. Nutrient stimulation of mesenteric blood flow - implications for older critically ill patients. World J Crit Care Med 2017;6(1):28-36
- Cotogni. Management of parenteral nutrition in critically ill patients. World J Crit Care Med 2017;6(1):13-20
- Raschi. Drug-induced liver injury: Towards early prediction and risk stratification. World J Hepatol 2017;9(1):30-37
- Rondon-Berrios. Hypertonicity: Clinical entities, manifestations and treatment. World J Nephrol 2017;6(1):1-13
- Heytens. Exertional rhabdomyolysis and heat stroke: Beware of volatile anesthetic sedation. World J Crit Care Med 2017;6(1):21-27
- Zaragoza. Current approach to disseminated intravascular coagulation related to sepsis - organ failure type. World J Hematol 2017;6(1):11-16
- Mizobata. Damage control resuscitation: a practical approach for severely hemorrhagic patients and its effects on trauma surgery. Journal of Intensive Care 2017;5:4
- Kushimoto. Acute traumatic coagulopathy and trauma-induced coagulopathy: an overview. Journal of Intensive Care 2017;5:6
- Sakamoto. Monitoring the coagulation status of trauma patients with viscoelastic devices. Journal of Intensive Care 2017 5:7
- Kudo. Permissive hypotension/hypotensive resuscitation and restricted/controlled resuscitation in patients with severe trauma. Journal of Intensive Care 2017;5:11
- Nishida. Tranexamic acid and trauma-induced coagulopathy. Journal of Intensive Care 2017;5:5
- Hayakawa. Dynamics of fibrinogen in acute phases of trauma. Journal of Intensive Care 2017;5:3
- Ishikura. Trauma-induced coagulopathy and critical bleeding: the role of plasma and platelet transfusion. Journal of Intensive Care 2017;5:2
- Cavaliere. A year in review in Minerva Anestesiologica 2016. Critical Care. Experimental and clinical studies. Minerva Anestesiologica 2017;83(1):108-20
- Berry. Hypertensive disorders in pregnancy. World J Nephrol 2016;5(5):418-428
SCCM Congress Plenary Articles
- Goligher. Physician-Assisted Suicide and Euthanasia in the ICU: A Dialogue on Core Ethical Issues. Crit Care Med 2017;45(2):149–155
- Buchman. Innovative Interdisciplinary Strategies to Address the Intensivist Shortage. Crit Care Med 2017;45(2):298–304
- Kochanek. The Brain and Hypothermia—From Aristotle to Targeted Temperature Management. Crit Care Med 2017;45(2):305–310
- Marshall. Global Collaboration in Acute Care Clinical Research: Opportunities, Challenges, and Needs. Crit Care Med 2017;45(2):311–320
- Ely. The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families. Crit Care Med 2017;45(2):321–330
- Roberts. Right Dose, Right Now: Customized Drug Dosing in the Critically Ill. Crit Care Med 2017;45(2):331–336
- Alverdy. Collapse of the Microbiome, Emergence of the Pathobiome, and the Immunopathology of Sepsis. Crit Care Med 2017;45(2):337–347
- Nadkarni. After the Fall: The Tapestry of Disturbance and Recovery. Crit Care Med 2017;45(2):348–355
- Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit Care Med 2017;epublished January 17th
- De Backer. Surviving Sepsis Guidelines. A Continuous Move Toward Better Care of Patients With Sepsis. JAMA 2017;epublished January 19th
- Howell. Management of Sepsis and Septic Shock. JAMA 2017;epublished January 19th
- Dellinger. A users’ guide to the 2016 Surviving Sepsis Guidelines. Intensive Care Med 2017;epublished January 18th
- Buchman. Practice guidelines as implementation science: the journal editorsʼ perspective. Intensive Care Med 2016;epublished January 18th
- Petrini. Perioperative and periprocedural airway management and respiratory safety for the obese patient: 2016 SIAARTI Consensus. Minerva Anestesiologica 2016;82(12):1314-35
- Muñoz. International consensus statement on the peri-operative management of anaemia and iron deficiency. Anaesthesia 2017;72:233–247
- Kapadia. Can less be more in intensive care?. Indian J Crit Care Med 2017;21:1-5
- Randall. Palliative Care in the ICU and the Role for Physician-Assisted Dying—Or Lack Thereof. Crit Care Med 2017;45(2):356-357
- Martin. More Food for Thought: Nutrition, the Nutrition Risk in the Critically Ill Score, and the Dilemma of “Goal” Feeding. Crit Care Med 2017;45(2):358-360
- Pickerodt. Long-Term Survival After Extracorporeal Membrane Oxygenation Therapy: The Attention It Deserves! Crit Care Med 2017;45(2):361-362
- Anderson. Bringing the ABCDEF Bundle to Life and Saving Lives Through the Process. Crit Care Med 2017;45(2):363-365
- Segall. ICU Rounds: “What We’ve Got Here Is Failure to Communicate”. Crit Care Med 2017;45(2):366-367
- Villar. Oxygen: Breath of Life or Kiss of Death. Crit Care Med 2017;45(2):368-369
- Mikkelsen. Triangulating Weakness, Morbidity, and Mortality Among Acute Respiratory Distress Syndrome Survivors: A Story Emerges. Crit Care Med
- Pena. Acetaminophen, the missing anion gap in the patient with metabolic acidosis. The Southwest Respiratory and Critical Care Chronicles 2017;5(17):32-37
- Singh. Ventricular tachycardia. Southwest Respiratory and Critical Care Chronicles 2017;5(17):38-41
- Watkins. Potential Pitfalls of Experimental Design. Southwest Respiratory and Critical Care Chronicles 2017;5(17):68-70
- Lee. Transparency and Trust — Online Patient Reviews of Physicians. N Engl J Med 2017;376:197-199
- Menikoff. The Common Rule, Updated. N Engl J Med 2017;epublished January 19th
- Moon. Powerful Ideas for Global Access to Medicines. N Engl J Med 2017;epublished January 18th
Once again the Critical Care Reviews Meeting will be discussing the biggest studies of the previous year with their chief investigators, asking the question "should we implement the results of this trial into our dialy practice?". We also have the John Hinds Trauma Lecture, delivered this year by Prof Donat Spahn (Zurich), lead for the new European Trauma Guideline, published a few months ago. Paul Marik thinks he has discovered "The Cure for Sepsis", while John Myburgh will explain the ins and outs of research methodology in the "Path to Truth". In addition, there is the very popular "How I Manage....." series of short talks from our speakers on conditions they are experts in, the "Year in Review" and the now famous "Informal Chat" in the bar after the main event.
Don't forget to register for dinner also, where the menu is based on an original menu from the only sailing the Titanic made. Registration for both the meeting and meal is available on the meeting webpage. The Critical Care Reviews Meeting is a not-for-profit event.
The first release of tickets for Das SMACC sold out in just 2.5 hours this week. The next opportunity will be on February 1st (depending on where you are in the world). If you haven't yet checked out the programme and workshops, then have a look on the SMACC website. The Hardcore Intensive Care workshop being organised by Steve Mathieu and Sarah Yong will cover all your critical care questions.
The Canadian Critical Care Conference (www.canadiancriticalcare.CA; @CriticalCareCa) is rather special. Not only a spectacular location (world famous Whistler, British Columbia, Canada) but also the world's finest downhill skiing, cross-country skiing, and mountain village location (did we mention it's in Whistler?). Located at the lovely Four Seasons Resort, we offer a meeting crammed with world renown speakers but in a more laid back, interactive, and reinvigorating setting that your typical medical conference. We cover all of the core science and latest research, but do not shy away from all those topics that make for a great, or not so great, patient care. This includes human factors, burnout and resilience, end-of-life care, multidisciplinary care, social media, organ donation, and the patient perspective. We are always kean to engage trainees and nurses, we offer world class precourses, and we ensure time to enjoy all that makes Whistler and Blackcomb so special. We have no desire to be the world's largest acute care conference. Rather we want to create something unique: an opportunity to learn; to interact, to have fun, and to leave more refreshed and engaged. Come and join us.
(Image from Chensiyuan via Wikipedia)
The Critical Care Symposium (CCS) was initiated to satisfy the purpose of creating a world-class environment for medical enrichment in the North of England, particularly in Manchester. It was envisioned as a common informal platform wherein professionals from the field of critical care could provide and enhance the knowledge of delegates on current practices and related fields of interest.
Now in its 14th year, the annual conference regularly has renowned speakers from around the world and attracts more than 400 delegates. And this year is no different. In recent years a parallel course on ultrasound has been conducted alongside the conference that provides ample hand-on experience over two days. This year will host the 7th Ultrasound in Acute Care. For more information please visit http://critcaresymposium.co.uk.
The ANZICS/ACCCN Annual Scientific Meeting, which incorporates the annual Paediatric and Neonatal Intensive Care Conference, will be held at the Gold Coast Convention and Exhibition Centre, 11-13 October 2017. The Annual Scientific Meeting will be the preeminent critical care conference in Australasia for the calendar year and will be an important platform that will allow doctors, nurses and allied health practitioners to meaningfully connect and discuss new developments and research in the field of intensive and critical care.
The theme of the Meeting is “Thinking Outside the Flags” and will focus upon innovative and challenging advances that lie outside the safe zone of current practice, as well as the potential dangers that they may bring. A number of highly regarded international speakers will join our distinguished national and local speakers, experts in the field of intensive care medicine, nursing and allied health, promising delegates an exciting and challenging program.
Registration and the call for abstracts will open on 20 March 2017. For further information or to express your interest in attending, please visit http://intensivecareasm2017.com.au/.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week