Welcome to the 227th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
It's a packed newsletter this week, whose highlights are the Brazilian CHECKLIST-ICU randomised controlled trial investigating checklists in the ICU, as well as three guidelines: the latest updated European guideline on management of major bleeding and coagulopathy following trauma, a German guideline on intravascular volume therapy in adults, and an AAGBI guideline on the use of blood components and their alternatives 2016. There are loads of great review articles to choose from, but if you only have time for one, try either this paper on personalizing mechanical ventilation for acute respiratory distress syndrome or this one on Intravenous Fluids in AKI: A Mechanistically Guided Approach.
As anticipation builds to SMACC DUB in just 10 weeks time, here's a taster as to what to expect, with the release of my SMACC Chicago debate with Paul Marik (who is coming to #CCR17) on predicting fluid responsiveness. Huge thanks to Scott Weingart for synching the audio to the animated movie. Also, a small number of print editions of the Critical Care Reviews Book 2016 are still available. They cost little more than the price of postage and packaging. The pdf is available as a free download.
Mac Sweeney vs Marik - Predicting Fluid Responsiveness is a Waste of Time
- Abstract: BRICNet. Effect of a Quality Improvement Intervention With Daily Round Checklists, Goal Setting, and Clinician Prompting on Mortality of Critically Ill Patients. A Randomized Clinical Trial (CHECKLIST-ICU). JAMA 2016;315(14):1480-1490
- Abstract: Eastwood. Targeted therapeutic mild hypercapnia after cardiac arrest: A phase II multi-centre randomised controlled trial (the CCC trial). Resuscitation 2016;epublished April 7th
- Abstract: Steiner. Fresh frozen plasma versus prothrombin complex concentrate in patients with intracranial haemorrhage related to vitamin K antagonists (INCH): a randomised trial. Lancet Neurology 2016;15(6):566–573
- Abstract: Matsuda. Effect of Cilostazol on Cerebral Vasospasm and Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage: A Randomized, Double-Blind, Placebo-Controlled Trial. Cerebrovasc Dis 2016;42(1-2):97-105
- Abstract: Johnson-Obaseki. Complication rates of open surgical versus percutaneous tracheostomy in critically ill patients. Laryngoscope 2016;epublished April 14th
- Abstract: Villablanca. Therapeutic hypothermia in ST elevation myocardial infarction: a systematic review and meta-analysis of randomised control trials. Heart 2016;102:712-719
- Abstract: Elmer. Association of early withdrawal of life-sustaining therapy for perceived neurological prognosis with mortality after cardiac arrest. Resuscitation 2016;102:127–135
- Editorial: Sandroni. Does early withdrawal of life-sustaining treatment increase mortality after cardiac arrest? Resuscitation 2016;102:A3-A4
- Full Text: Shankar-Hari. Evidence for a causal link between sepsis and long-term mortality: a systematic review of epidemiologic studies. Critical Care 2016;20:101
- Full Text: Póvoa. Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study. Ann Intensive Care 2016;6(1):32
- Full Text: Garrouste-Orgeas. Treatment intensity and outcome of nonagenarians selected for admission in ICUs: a multicenter study of the Outcomerea Research Group. Annals of Intensive Care 2016;6:31
- Abstract: De Waele. Decompressive laparotomy for abdominal compartment syndrome. Br J Surg 2016;103:709–715
- Schött. The endothelial glycocalyx and its disruption, protection and regeneration: a narrative review. Scand J Trauma Resusc Emerg Med 2016;24:48
- Spiegel. Stressed vs. unstressed volume and its relevance to critical care practitioners. Clin Exp Emerg Med 2016;3(1):52-54
- Squiers. Contemporary extracorporeal membrane oxygenation therapy in adults: Fundamental principles and systematic review of the evidence. J Thorac Cardiovasc Surg 2016;epublished March 12th
- Fox. Troponin assay use in the emergency department for management of patients with potential acute coronary syndrome: current use and future directions. Clin Exp Emerg Med. 2016;3(1):1-8
- Hahn. The half-life of infusion fluids: An educational review. Eur J Anaesthesiol 2016;epublished April 7th
- Petitpas. Use of intra-osseous access in adults: a systematic review. Crit Care 2016;20:102
- Berngard. Personalizing mechanical ventilation for acute respiratory distress syndrome. J Thorac Dis 2016;8(3):E172-E174
- Feldman. Corticosteroids in the adjunctive therapy of community-acquired pneumonia: an appraisal of recent meta-analyses of clinical trials. J Thorac Dis 2016;8(3):E162-E171
- Li. Management of large mediastinal masses: surgical and anesthesiological considerations. J Thorac Dis 2016;8(3):E175-E184
- Del Sorbo. Non-invasive ventilation in immunocompromised patients with acute hypoxemic respiratory failure. J Thorac Dis 2016;8(3):E208-E216
- Ingelse. Pediatric Acute Respiratory Distress Syndrome: Fluid Management in the PICU. Front Pediatr 2016;4:21
- Im. Pediatric Acute Respiratory Distress Syndrome: Fibrosis versus Repair. Front Pediatr 2016;4:28
- Stephen. Acute mesenteric ischemia: The what, why, and when?. Indian J Vasc Endovasc Surg 2016;3:24-8
- Ralto. Mitochondria in Acute Kidney Injury. Semin Nephrol 2016;36(1):8-16
- Mulay. Targeting Inflammation in So-Called Acute Kidney Injury. Semin Nephrol 2016;36(1):17–30
- Molitoris. Quantifying Glomerular Filtration Rates in Acute Kidney Injury: A Requirement for Translational Success. Semin Nephrol 2016;36(1):31–41
- Weisbord. Design of Clinical Trials in Acute Kidney Injury: Lessons from the Past and Future Directions. Semin Nephrol 2016;36(1):42–52
- Legrand. Intravenous Fluids in AKI: A Mechanistically Guided Approach. Semin Nephrol 2016;36(1):53–61
- Walker. Targeting Iron Homeostasis in Acute Kidney Injury. Semin Nephrol 2016;36(1):62–70
- Romagnoli. Novel Extracorporeal Therapies for Combined Renal-Pulmonary Dysfunction. Semin Nephrol 2016;36(1):71–77
- Wald. The Timing of Renal Replacement Therapy Initiation in Acute Kidney Injury. Semin Nephrol 2016;36(1):78-84
- Mazzone. Mending a broken heart but breaking the kidney. Nephrology 2016;epublished April 15th
- Bedreag. New perspectives of volemic resuscitation in polytrauma patients: a review. Burns & Trauma 2016;4:5
- Banyard. Endothelial progenitor cells and burn injury – exploring the relationship. Burns & Trauma 2016;4:4
- Chua. Skin tissue engineering advances in severe burns: review and therapeutic applications. Burns & Trauma 2016;4:3
- Voldby. Fluid therapy in the perioperative setting—a clinical review. Journal of Intensive Care 2016;4:27
- Rossaint. The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition. Critical Care 2016;20:100
- Intravascular volume therapy in adults: Guidelines from the Association of the Scientific Medical Societies in Germany. Eur J Anaesthesiol 2016;epublished April 7th
- Klein. AAGBI guidelines: the use of blood components and their alternatives 2016. Anaesthesia 2016;epublished April 8th
- Various. Complications of Central Venous Catheterization. N Engl J Med 2016;374:1489-1492
- Dalton. Other anaesthetic uses of fibreoptic bronchoscopy. Anaesthesia 2016;71:591–592
- Heidegger. Time to stand up for fibreoptic intubation. Anaesthesia 2016;71:592–593
- Ward. Training in fibreoptic intubation – I. Anaesthesia 2016;71:593
- Bell. Training in fibreoptic intubation – 2. Anaesthesia 2016;71:593–594
- Schechtman. Time to abandon fibreoptic intubation? Not yet. Anaesthesia 2016;71:594–595
- Ahmad. Abandoning awake fibreoptic bronchoscopy – a reply. Anaesthesia 2016;71:595–596
- Li. Veno-venous extracorporeal membrane oxygenation support during lung volume reduction surgery for a severe respiratory failure patient with emphysema. J Thorac Dis 2016;8(3):E240-E243
- Saxena. Acute fibrinous and organizing pneumonia: A rare form of nonbacterial pneumonia. Indian J Crit Care Med 2016;20:245-7
- Pandharikar. Chest trauma: A case for single lung ventilation. Indian J Crit Care Med 2016;20:248-50
The Irish Critical Care-Clinical Trials Group (ICC-CTG) host a two hour meeting in conjunction with the Intensive Care Society of Ireland Annual Meeting in the AVIVA Stadium on Saturday June 11th and two Clinical Research Foundation Workshops on Sunday June 12th & Monday June 13th. A distinguished international panel of guests will be present to demonstrate how a CTG functions and what each unit needs to know. In addition, this meeting provides the opportunity to network and keep up to speed with the ICC-CTG's current and future trials portfolio.
A networking dinner will be hosted on Monday 13th June in Sophie's Restaurant at The Dean Hotel. These meetings will be immediately before SMACC Dub and may also be of interest to those visiting Dublin. The registration fee is €50 and includes lunch & refreshments throughout the day. Book before 1st May to avail of the Early Bird option of €30 (limited availability).
Please contact Louise at firstname.lastname@example.org to register for the meeting and meal.
The Summer Scientific Meeting of the Intensive Care Society is on Saturday June 11th at the Aviva Stadium, the home of Irish Rugby and Soccer. The theme is toxicology and features several of the SMACC faculty who will be in town that weekend. Registration hasn't yet opened, but the meeting programme is available here.
The 13th Annual Critical Care Symposium is on April 28th and 29th in Manchester Town Hall, England. This meeting aims to bring together world renowned speakers for a conference outside London and to provide a conducive environment allowing informal discussion. Most importantly, this event provides good quality education covering various topics in Intensive Care at an affordable price.
The 9th UK Critical Care Research Forum is being held on 23rd – 24th June 2016 at the Sage Gateshead, with over 20 research proposals as well as sessions on adaptive trial design, international collaborations in critical care trials and patient-centred research. There is also a Forum dinner at the Baltic Centre for Contemporary Art. Registration is now open.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week