Welcome to the 207th Critical Care Reviews Newsletter, bringing you the best critical care research published in the past week, plus a wide range of free full text review articles, guidelines, commentaries, editorials, study critiques, correspondence and case reports from hundreds of clinical and scientific journals. It's a small newsletter this week, whose highlights are two randomized controlled trials on refeeding syndrome and humidified high-flow nasal oxygen, plus review articles on perioperative myocardial infarction/injury after noncardiac surgery and urgent chemotherapy in hematological patients in the ICU. If you only have time to read one paper this week, try this one on haemodynamic effects of lung recruitment manoeuvres.
There are only 8 days until the UK Intensive Care Society's State of the Art Meeting, with a massive range of speakers and, for the first time, fully embracing FOAM and social media. There are free downloads, podcasts, Twitter moderators at every session, and a social media discussion panel at the opening plenary. The full programme is available here. I hope to see you in London.
In keeping with the #ICSSOA15 theme, this week's Topic of the Week focuses on the third of the three way ARDS debates, this time between Eddy Fan and Luciano Gattinoni, on "ECMO - You're Doing it Wrong", starting with a paper on cannulation strategies in tomorrow's Paper of the Day.
In other meeting news, the second allocation of registrations for SMACC Dublin opens in less than 48 hours. Wherever you are in the world, don't get caught out with differences in time zones, as I managed this week (sorry guys). These tickets will sell out in just a few hours.
- Abstract: Doig. Restricted versus continued standard caloric intake during the management of refeeding syndrome in critically ill adults: a randomised, parallel-group, multicentre, single-blind controlled trial. Lancet Respir Med 2015;epublished November 16th
- Abstract: Jones. Randomized Controlled Trial of Humidified High-Flow Nasal Oxygen for Acute Respiratory Distress in the Emergency Department: The HOT-ER Study. Respir Care 2015;epublished November 17th
- Abstract: Navarro. Prehospital treatment with levetiracetam plus clonazepam or placebo plus clonazepam in status epilepticus (SAMUKeppra): a randomised, double-blind, phase 3 trial. Lancet Neurology 2015;epublished November 25th
- Full text: Greau. Automatic versus manual changeovers of norepinephrine infusion pumps in critically ill adults: a prospective controlled study. Annals of Intensive Care 2015;5:40
- Abstract: Hong. Effect of Intravascular Ultrasound–Guided vs Angiography-Guided Everolimus-Eluting Stent Implantation: The IVUS-XPL Randomized Clinical Trial. JAMA 2015;314(20):2155
- Full Text: Vet. A randomized controlled trial of daily sedation interruption in critically ill children. Intensive Care Med 2015;epublished November 24th
- Abstract: Kim. The Effects of Chlorhexidine Gluconate Bathing on Healthcare-Associated Infection in Intensive Care Units: A Meta-analysis. J Crit Care 2015;epublished November 20th
- Full Text: Nseir. Continuous control of tracheal cuff pressure for VAP prevention: a collaborative meta-analysis of individual participant data. Annals of Intensive Care 2015;5:43
- Abstract: O’Connor. Incidence and associations of acute kidney injury after major abdominal surgery. Intensive Care Med 2015;epublished November 24th
- Full text: Guérin. Effects of passive leg raising and volume expansion on mean systemic pressure and venous return in shock in humans. Critical Care 2015;19:411
- Abstract: Darmon. Acute kidney injury in critically ill patients with haematological malignancies: results of a multicentre cohort study from the Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologie. Nephrol Dial Transplant 2015;30:2006-2013
- Abstract: Ehrmann. Aerosol therapy in intensive and intermediate care units: prospective observation of 2808 critically ill patients. Intensive Care Med 2015;epublished November 24th
- Hazeldine. Traumatic Brain Injury and Peripheral Immune Suppression: Primer and Prospectus. Front Neurol 2015;6:235
- Seitz. Recovery Potential After Acute Stroke. Front Neurol 2015;6:238
- Napp. Cannulation strategies for percutaneous extracorporeal membrane oxygenation in adults. Clin Res Cardiol 2015;epublished November 25th
- Puelacher. Perioperative myocardial infarction/injury after noncardiac surgery. Swiss Med Wkly. 2015;145:w14219
- Vazira. Decongestion: Diuretics and other therapies for hospitalized heart failure. Indian Heart Journal 2015;epublished November 24th
- Lovas. Haemodynamic Effects of Lung Recruitment Manoeuvres. BioMed Research International 2015;2015:478970
- Verges. Hypoxic conditioning as a new therapeutic modality. Front Pediatr 2015;3:58
- Logue. Minimally Invasive Necrosectomy Techniques in Severe Acute Pancreatitis: Role of Percutaneous Necrosectomy and Video-Assisted Retroperitoneal Debridement. Gastroenterology Research and Practice;2015:693040
- Borody. Fecal microbiota transplantation in gastrointestinal diseases. Pol Arch Med Wewn 2015;125(11):852-858
- Rajesh. Imaging Diagnosis of Splanchnic Venous Thrombosis. Gastroenterol Res Pract 2015;2015:101029
- Mirrakhimov. Hypercalcemia of malignancy: An update on pathogenesis and management. North Am J Med Sci 2015;7:483-93
- Moors. Urgent chemotherapy in hematological patients in the ICU. Curr Opin Crit Care 2015;21(6):559-568
- van Gorp. New Insights into the Pros and Cons of the Clinical Use of Vitamin K Antagonists (VKAs) Versus Direct Oral Anticoagulants (DOACs). Nutrients 2015;7(11):9538-9557
- Carr. Ascorbate-dependent vasopressor synthesis: a rationale for vitamin C administration in severe sepsis and septic shock? Critical Care 2015;19:418
- Klučka. Controversies in Pediatric Perioperative Airways. BioMed Research International 2015;2015:368761
- Li. Pediatric open globe injury: A review of the literature. J Emerg Trauma Shock 2015;8:216-23
- Nunes. Brazilian consensus on anesthetic depth monitoring. Rev Bras Anestesiol 2015;65(6):427-436
- Checketts. Recommendations for standards of monitoring during anaesthesia and recovery 2015 : Association of Anaesthetists of Great Britain and Ireland. Anaesthesia 2015;epublished November 19th
- Feitosa-Filho. SBC Guidelines on Unstable Angina and Non-ST-Elevation Myocardial Infarction: Executive Summary. Arq Bras Cardiol 2015;105(3):214–227
- Hirsch. The medical response to multisite terrorist attacks in Paris. Lancet 2015;epublished November 24th
- Quaglio. Ebola: lessons learned and future challenges for Europe. Lancet Infectious Diseases 2015;epublished October 25th
- Rodigin. An update on emergency care and emergency medicine in Russia. International Journal of Emergency Medicine 2015;8:42
- Wevers. Twiddler syndrome mimicking an abdominal aortic aneurysm. Netherlands Heart Journal 2015;23(12):611-612
- Kuiper. An unexpected ECG finding. Netherlands Heart Journal 2015;23(12):613-616
- Alonso-Fernández. Cardiac and Pulmonary Ultrasound for Diagnosing TRALI. Case Rep Crit Care 2015;2015:362506
Due to hugely successful previous events, the Critical Care Reviews Meeting 2016 has been moved to a brand new venue, the stunning, multi-million pound Titanic Centre, birthplace of RMS Titanic, As before, the meeting theme is to review the biggest studies of the previous year, with chief investigators present where possible to discuss their work in person. From Wellington, New Zealand, Dr Paul Young will talk on his studies SPLIT (saline versus plasmalyte) and HEAT (paracetamol for pyrexia control). Dr John Holcomb (Houston, USA) will review his mega trial PROPPR, evaluating blood product transfusion ratios in traumatic haemorrhage. Dr Anthony Gordon (London, England), will review his VANISH study, a multi-centre randomized controlled trial comparing vasopressin with noradrenaline, with or without hydrocortisone, for first-line vasopressor support in septic shock. Prof Tim Walsh (Edinburgh, Scotland) will review the ABLE study, including his ABLE UK component, evaluating age of transfused red cells, as well as RECOVER, a post-ICU rehab study. In addition, two of the most eminent intensivists in global critical care, Prof Jean-Louis Vincent (Brussels, Belgium) and Prof Luciano Gattinoni (Milan, Italy) will be on hand to discuss the significance of these findings. A new feature for the meeting is the John Hinds' Trauma Lecture, with Dr Brian Burns (Sydney HEMS, Australia) travelling across the world to deliver the inaugural presentation. It won't be all study discussion, with other elements to the meeting, including the spectacularly popular "Informal Chat", taking place that evening.
If you haven't yet attended this modern, niche meeting, then put the date Friday January 29th in your diary. Both delegate and speaker feedback from previous meetings has been incredibly positive, allowing the event to grow and attract some of the biggest names in critical care. The Titanic Centre is just minutes from Belfast City Airport, with a hotel within 3 minutes walking distance, and is a 20 minute walk from the city centre, including the Cathedral Quarter, Belfast's cultural centre full of great restaurants and pubs. Further details regarding delegate rate accommodation should be available in the next week or two. Talks are given in the setting of the rebuilt famous staircase from the great ship, while both the "Informal Chat" session and dinner overlook the floodlit slipways where Titanic and Olympic were launched. Ton finish a fantastic day, we have a pre-dinner talk from a colleague of mine, Mr Chris Andrews, on "My Great Great Uncle Thomas Andrews - The Man Who Built Titanic".
With some exciting new innovations planned, this new meeting promises to delivery on its burgeoning reputation. Don't wait too long before registering, as numbers are capped to keep this an intimate event. It is as strong a one day programme as you could possibly find. If you think your colleagues would find this event interesting, please circulate this information - this is a not-for-profit event, run in association with the Northern Ireland Intensive Care Society.
The next SMACC Conference is on June 13th to 16th, in Dublin, Ireland. Registration opened on October 28th, sold out in a few hours, and closed again. Luckily, there are two further smaller batches of tickets available on Wednesday December 2nd and Wednesday February 3rd. With world leading academics and high profile clincians from the FOAMed critical care world, this conference fuses knowledge, dynamism and enthusiasm with an altruisitic desire to be the best we can be for the benefit of our patients. It's the most fun, modern critical care conference in the world. If you've been lucky enough to register for #smaccDUB, the presentations from SMACC Chicago, which are now online at Intensive Care Network, will give you an idea as to what to expect.
(Image from Wikimedia)
This year's State-of-the-Art Meeting promises an exciting programme in a new dynamic format. It aims to be the first major national society to fully embrace social media and free open access medical education, with an opening plenary session and a workshop, as well full integration of Twitter questions into sessions, live blogging, and open-access AV materials.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week