Welcome to the 203rd Critical Care Reviews Newsletter, bringing you the best critical care research published in the past week, plus a wide range of free full text review articles, guidelines, commentaries, editorials, study critiques, correspondence and case reports from hundreds of clinical and scientific journals.
It's a short newsletter this week, with its highlights being a randomized controlled trial investigating glutamine-supplemented parenteral nutrition in surgical ICU patients, plus review articles on neuro-ophthalmological emergencies, inhalation injury and prehospital trauma ultrasound. This week's Topic of the Week is central nervous system trauma, starting with a paper on the role of invasive monitoring in traumatic brain injury in tomorrow's Paper of the Day.
In other news, this weekend's Rugby World Cup Final was deservedly won by the New Zealand All Blacks; however, it was this incredibly generous gesture from Sonny Bill Williams which captured the world's attention and admiration.
If you missed out on registration for SMACC Dublin, then you won't want to miss out on the other critical care FOAMed meeting in Ieland next year - The Critical Care Reviews Meeting in January. We discuss the biggest studies of the year, with chief investigators present to talk about their work in person. Numbers are capped to keep this a small intimate event, so don't delay too long before booking. You won't want to be disappointed twice.
- Abstract: Ziegler. Efficacy and Safety of Glutamine-supplemented Parenteral Nutrition in Surgical ICU Patients: An American Multicenter Randomized Controlled Trial. Ann Surg 2015;epublished October 22nd
- Abstract: Sabaté. Clinical outcomes in patients with ST-segment elevation myocardial infarction treated with everolimus-eluting stents versus bare-metal stents (EXAMINATION): 5-year results of a randomised trial. Lancet 2015;epublished October 28th
- Abstract: Mitchell. Risk of organism acquisition from prior room occupants: a systematic review and meta-analysis. Journal of Hospital Infection 2015;91(3):211–217
- Full Text: Bossers. Experience in Prehospital Endotracheal Intubation Significantly Influences Mortality of Patients with Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis. PLOS ONE 2015;epublished October 23rd
- Abstract: McPhail. Ability of King's College Criteria and Model for End-stage Liver Disease Scores to Predict Mortality of Patients with Acute Liver Failure: A Meta-Analysis. Clinical Gastroenterology and Hepatology 2015;epublished October 21st
- Abstract: Egal. Targeting Oliguria Reversal in Goal-Directed Hemodynamic Management Does Not Reduce Renal Dysfunction in Perioperative and Critically Ill Patients: A Systematic Review and Meta-Analysis. Anesth Analg 2015;epublished October 26th
- Abstract: Schouten. Incidence and Mortality of Acute Respiratory Distress Syndrome in Children: A Systematic Review and Meta-Analysis. Crit Care Med 2015;epublished October 27th
- Abstract: Meduri. Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients' data from four randomized trials and trial-level meta-analysis of the updated literature. Intensive Care Med 2015;epublished October 27th
- Abstract: Dempsey. Long-Term Outcome Following Tracheostomy in Critical Care: A Systematic Review. Crit Care Med 2015;epublished October 26th
- Abstract: Lameijer. Mechanical cardiopulmonary resuscitation in in-hospital cardiac arrest: a systematic review. European Journal of Emergency Medicine 2015;22(6):379-383
- Abstract: Tusman. The Sensitivity and Specificity of Pulmonary Carbon Dioxide Elimination for Noninvasive Assessment of Fluid Responsiveness. Anesth Analg 2015;epublished October 26th
- Full Text: Papachristofi. The contribution of the anaesthetist to risk-adjusted mortality after cardiac surgery. Anaesthesia 2015;epublished October 28th
- Abstract: Inaba. FAST ultrasound examination as a predictor of outcomes after resuscitative thoracotomy: a prospective evaluation. Ann Surg 2015;262(3):512-8
- Abstract: Carteaux. Failure of Noninvasive Ventilation for De Novo Acute Hypoxemic Respiratory Failure: Role of Tidal Volume. Crit Care Med 2015;epublished October 26th
- Free Text: Tagami. Low-dose corticosteroid treatment and mortality in refractory abdominal septic shock after emergency laparotomy. Annals of Intensive Care 2015;5:32
- Abstract: Yaghi. Treatment and Outcome of Thrombolysis-Related Hemorrhage: A Multicenter Retrospective Study. JAMA Neurol 2015;epublished October 26th
- Full Text: Ma. Temporal Trends in Mortality in the United States, 1969-2013. JAMA 2015;314(16):1731
- Abstract: Allegretti. Prognosis of Acute Kidney Injury and Hepatorenal Syndrome in Patients with Cirrhosis: A Prospective Cohort Study. International Journal of Nephrology 2015;2015:108139
- Abstract: Koenig. Safety of Propofol as an Induction Agent for Urgent Endotracheal Intubation in the Medical Intensive Care Unit. J Intensive Care Med December 2015;30:499-504
- Abstract: Stehman. Association between blood alcohol concentration and mortality in critical illness. J Crit Care 2015;epublished September 2nd
- Abstract: Iwashyna. Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care. Am J Respir Crit Care Med 2015;192(9):1045-1051
- Abstract: Goligher. Evolution of Diaphragm Thickness during Mechanical Ventilation. Impact of Inspiratory Effort. Am J Respir Crit Care Med 2015;192(9):1080-1088
- Full Text: Munoz-Bendix. Extracorporeal decarboxylation in patients with severe traumatic brain injury and ARDS enables effective control of intracranial pressure. Critical Care 2015;19:381
- Batterink. Pharmacological interventions for the acute management of hyperkalaemia in adults. Cochrane Database Syst Rev 2015;epublished October 27th
- Lemos. Neuro-Ophthalmological Emergencies. Neurohospitalist 2015;5(4):223–233
- King. Dabigatran-Associated Intracranial Hemorrhage: Literature Review and Institutional Experience. Neurohospitalist 2015;5(4):234–244Neurohospitalist 2015;5(4):234–244
- Rajagopal. Differential regulation of volatile anesthetics on ion channels. Int J Nutr Pharmacol Neurol Dis 2015;5:128-34
- Gaspar. The Role of Focused Echocardiography in Pediatric Intensive Care: A Critical Appraisal. BioMed Research International 2015;2015:596451
- Poelaert. Assessment of loading conditions with cardiac ultrasound. A comprehensive review. Anaesthesiol Intensive Ther 2015;epublished October 27th
- Santos. Cardiovascular imaging: what have we learned from animal models? Front Pharmacol 2015;epublished October 21st
- Anand. Durable Mechanical Circulatory Support versus Organ Transplantation: Past, Present, and Future. BioMed Research International 2015;2015:849571
- Mahmoud. Risk of Bleeding in End-Stage Liver Disease Patients Undergoing Cardiac Catheterization. Texas Heart Institute Journal 2015;42(5):414-418
- Agnetti. New Insights in the Diagnosis and Treatment of Heart Failure. BioMed Research International 2015;2015:265260
- Smith. Brugada Syndrome: A Review of Perioperative Management For Anesthesiologists. Anesthesiology News 2015;41:105
- Mooney. Evolution from electrophysiologic to hemodynamic monitoring: the story of left atrial and pulmonary artery pressure monitors. Front Physiol 2015;6:271
- Adegunsoye. Novel Therapeutic Strategies for Reducing Right Heart Failure Associated Mortality in Fibrotic Lung Diseases. BioMed Research International 2015;2015:929170
- Walker. Diagnosis and management of inhalation injury: an updated review. Critical Care 2015;19:351
- Cillóniz. Polymicrobial community-acquired pneumonia: An emerging entity. Respirology 2015;epublished October 23rd
- Levesquea. Current use and perspective of indocyanine green clearance in liver diseases. Anaesthesia Critical Care & Pain Medicine 2015;epublished October 21st
- Bernardi. Mechanisms of decompensation and organ failure in cirrhosis: From peripheral arterial vasodilation to systemic inflammation hypothesis. Journal of Hepatology 2015;63(5):1272–1284
- Velissarisa. Hypomagnesemia in Critically Ill Sepsis Patients. J Clin Med Res 2015;7(12):911-918
- Korsak. New Options of Apheresis in Renal Diseases: How and When. Blood Purif 2016;41:1-10
- Qavi. Clinical Use of Diuretics in Heart Failure, Cirrhosis, and Nephrotic Syndrome. International Journal of Nephrology 2015;2015:975934
- Kingma. Renocardiac syndromes: physiopathology and treatment stratagems. Can J Kidney Health Dis 2015;2:41
- Gorog. Platelet Function Tests: Why They Fail to Guide Personalized Antithrombotic Medication. J Am Heart Assoc 2015;4(5):e002094
- Morin. HDL in sepsis – risk factor and therapeutic approach. Front Pharmacol 2015;epublished October 23rd
- Lia. Research progress of acute coagulopathy of trauma-shock. Chin J Traumatol 2015;18(2):95–97
- O’Dochartaigha. Prehospital ultrasound of the abdomen and thorax changes trauma patient management: A systematic review. Injury 2015;46(11):2093–2102
- Amaefule. Operability in polytrauma. Arch Int Surg 2015;5:131-6
- Haldar. Rave drugs and anesthesiology practice: A pharmacoclinical review. Int J Nutr Pharmacol Neurol Dis 2015;5:135-40
- Feng. Critical importance of tracheal tube cuff pressure management. World J Anesthesiol 2015;4(2):10-12
- Portillo. New tools, new tick-borne diseases? World J Clin Infect Dis 2015;5(3):51-54
- Anderloni. Role and timing of endoscopy in acute biliary pancreatitis. World J Gastroenterol 2015;21(40):11205-11208
- Zhou. Pathogenesis, diagnosis and treatment of cerebral fat embolism. Chin J Traumatol 2015;18(2):120-3
- Maciel. The Reversal Sign. An Ominous Imaging Finding. Neurohospitalist 2015;5(4):251–252
- Gupta. Why is an IABP not the Answer to Cardiogenic Shock after Percutaneous Coronary Intervention? Is it that Noradrenaline helps, Especially by Improving the RV Function in Addition to LV Function? A View Point. J Vasc Med Surg 2015;3:220
- This weekend's Rugby World Cup Final was deservedly won by the New Zealand All Blacks; however, it was this incredibly generous gesture from Sonny Bill Williams which has captured the world's attention and admiration.
Due to hugely successful previous events, the Critical Care Reviews Meeting 2016 has been moved to a brand new venue, the stunning, multi-million pound Titanic Centre, birthplace of RMS Titanic, As before, the meeting theme is to review the biggest studies of the previous year, with chief investigators present where possible to discuss their work in person. From Wellington, New Zealand, Dr Paul Young will talk on his studies SPLIT (saline versus plasmalyte) and HEAT (paracetamol for pyrexia control). Dr John Holcomb (Houston, USA) will review his mega trial PROPPR, evaluating blood product transfusion ratios in traumatic haemorrhage. Dr Anthony Gordon (London, England), will review his VANISH study, a multi-centre randomized controlled trial comparing vasopressin with noradrenaline, with or without hydrocortisone, for first-line vasopressor support in septic shock. Prof Tim Walsh (Edinburgh, Scotland) will review the ABLE study, including his ABLE UK component, evaluating age of transfused red cells, as well as RECOVER, a post-ICU rehab study. In addition, two of the most eminent intensivists in global critical care, Prof Jean-Louis Vincent (Brussels, Belgium) and Prof Luciano Gattinoni (Milan, Italy) will be on hand to discuss the significance of these findings. A new feature for the meeting is the John Hinds' Trauma Lecture, with Dr Brian Burns (Sydney HEMS, Australia) travelling across the world to deliver the inaugural presentation. It won't be all study discussion, with other elements to the meeting, including the spectacularly popular "Informal Chat", taking place that evening.
If you haven't yet attended this modern, niche meeting, then put the date Friday January 29th in your diary. Both delegate and speaker feedback from previous meetings has been incredibly positive, allowing the event to grow and attract some of the biggest names in critical care. The Titanic Centre is just minutes from Belfast City Airport, with a hotel within 3 minutes walking distance, and is a 20 minute walk from the city centre, including the Cathedral Quarter, Belfast's cultural centre full of great restaurants and pubs. Further details regarding delegate rate accommodation should be available in the next week or two. Talks are given in the setting of the rebuilt famous staircase from the great ship, while both the "Informal Chat" session and dinner overlook the floodlit slipways where Titanic and Olympic were launched. With some exciting new innovations planned, this new meeting promises to delivery on its burgeoning reputation. Don't wait too long before registering, as numbers are capped to keep this an intimate event. It is as strong a one day programme as you could possibly find. If you think your colleagues would find this event interesting, please circulate this information - this is a not-for-profit event, run in association with the Northern Ireland Intensive Care Society.
The next SMACC Conference is on June 13th to 16th, in the Dublin Convention Centre, Ireland. Registration opened on October 28th, sold out in a few hours, and closed again. Luckily, there are two further smaller batches of tickets available on Wednesday December 2nd and Wednesday February 3rd. With world leading academics and high profile clincians from the FOAMed critical care world, this conference fuses knowledge, dynamism and enthusiasm with an altruisitic desire to be the best we can be for the benefit of our patients, rather than our wallets. It's the most fun, modern critical care conference in the world. If you've been lucky enough to register for #smaccDUB, the presentations from SMACC Chicago, which are now online at Intensive Care Network, will give you an idea as to what to expect. (Image from Wikimedia)
This year's State-of-the-Art Meeting promises an exciting programme in a new dynamic format. It aims to be the first major national society to fully embrace social media and free open access medical education, with an opening plenary session and a workshop, as well full integration of Twitter questions into sessions, live blogging, and open-access AV materials.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week