Newsletter 163 / January 18th 2015
Welcome to the 163rd Critical Care Reviews Newsletter, bringing you the best critical care research published in the past week, plus a wide range of free full text review articles, guidelines, commentaries, editorials, study critiques, correspondence and case reports from hundreds of clinical and scientific journals. It's a relatively short newsletter, as the upcoming Critical Care Reviews Meeting this Friday assumes greater importance. As such, for this week's Topic of the Week, we look ahead to some of the talks being given at the Meeting, starting with a paper on vitamin D deficiency in the critically ill in tomorrow's Paper of the Day.
Critical Care Reviews Meeting 2015
After almost a year of planning, the Critical Care Reviews Meeting 2015, discussing the hottest trials of 2014 is finally here. Studies being reviewed include the mechanical chest compression device studies CIRC and LINC; ALBIOS, investigating albumin in sepsis; TRISS, evaluating red cell transfusion thresholds in septic shock; OPTIMISE, looking at perioperative goal-directed haemodynamic therapy; SEPSISPAM, examining blood pressure targets in septic shock, PEITHO, exploring fibrinolysis in intermediate-risk PE, and a comparison of cerebral perfusion pressure-targeted therapy versus intracranial pressure-targeted therapy for raised intracranial pressure in paediatric CNS Infections. Chief investigators for three of the major RCTs presented at the Hot Topics Session of the European Society of Intensive Care Medicine meeting in Barcelona in October are present to discuss their work (CALORIES, HARP 2, VITdAL-ICU), as is the chief investigator for TTM. 2014 is the year of the early goal-directed sepsis therapy studies, and the chief investigator for ProMISe will be on hand to discuss the results of & ARISE, as well as give an insight into the yet to finish UK sepsis study ProMISe. If this wasn't enough, there are also review talks from world experts on early mobilisation, ECMO, airway management, sepsis and neuroprognostication post cardiac arrest. Regardless if you're a believer in, or skeptic of, evidence-based medicine, you'll be amazed by the discussion on this recent paper exposing the fragility of the science we base our practice on.
The programme is available and online registration is open. With a global array of speakers, including the chief investigators for some of the biggest studies of the past 12 months, this is one of the most contemporary meetings around. If you've been waiting to register, time is running out, so please do so today. Please feel free to contact me if you're thinking about making the trip - it would be great to hear from you.
The next SMACC conference will be held June 23rd to 26th, in Chicago, USA. Just like the Critical Care Reviews Meeting, this is a not-for-profit event, run by a team interested in sharing knowledge in a fun, modern way. It's a conference like no other. Further details will be out soon on the SMACC website.
Critical Care Horizons
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. A call for papers has been issued, so if you have something interesting to say, and can say it in an engaging manner, please get in touch. The first papers are currently being prepared.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
- Abstract: Al-Khafaji. Protocolized fluid therapy in brain-dead donors: the multicenter randomized MOnIToR trial. Intensive Care Med 2015;epublished January 13th
- Abstract: Miller. Low-dose Ketamine Versus Morphine for Acute Pain In the Emergency Department A Randomized Controlled Trial. Am J Emer Med 2015;epublished January 6th
- Abstract: Philippart. Randomized Intubation with Polyurethane or Conical Cuffs to Prevent Pneumonia in Ventilated Patients. Am J Respir Crit Care Med 2015;epublished January 13th
- Abstract: Ebinger. Effects of Golden Hour Thrombolysis. A Prehospital Acute Neurological Treatment and Optimization of Medical Care in Stroke (PHANTOM-S) Substudy. JAMA Neurol 2015;72(1):25-30
- Abstract: Lavigne-Lissalde. Recombinant human FVIIa for reducing the need of invasive second-line therapies in severe refractory postpartum hemorrhage:A multicenter, randomized, open controlled trial. Journal of Thrombosis and Haemostasis 2015;epublished January 16th
- Abstract: Nemeth. Bacteriostatic versus bactericidal antibiotics for patients with serious bacterial infections: systematic review and meta-analysis. J Antimicrob Chemother 2015;70:382-395
- Full Text: Gandhi. New-onset atrial fibrillation in sepsis is associated with increased morbidity and mortality. Netherlands Heart Journal 2015;epublished January 9th
- Full Text: Zangrillo. Preoperative intra aortic balloon pump to reduce mortality in coronary artery bypass graft: a meta-analysis of randomized controlled trials. Critical Care 2015;19:10
- Full Text: Fargen. A meta-analysis of prospective randomized controlled trials evaluating endovascular therapies for acute ischemic stroke. J NeuroIntervent Surg 2015;7:84-89
- Abstract: Yamakawa. Recombinant human soluble thrombomodulin in severe sepsis: a systematic review and meta-analysis. Journal of Thrombosis and Haemostasis 2015;epublished January 15th
- Abstract: Needham. Timing of Low Tidal Volume Ventilation and Intensive Care Unit Mortality in Acute Respiratory Distress Syndrome. A Prospective Cohort Study. Am J Respir Crit Care Med 2015;191(2):177-185
- Abstract: Landesberg. Myocardial dysfunction in severe sepsis and septic shock – no correlation with inflammatory cytokines in real-life clinical setting. Chest 2015;epublished January 15th
- Abstract: Peev. Causes and Consequences of Interrupted Enteral Nutrition: A Prospective Observational Study in Critically Ill Surgical Patients. JPEN J Parenter Enteral Nutr 2015;39(1):21-27
- Abstract: Braunschweig. Intensive Nutrition in Acute Lung Injury. A Clinical Trial (INTACT). JPEN J Parenter Enteral Nutr January 2015;39(1):13-20
- Abstract: Mokart. Prognosis of neutropenic patients admitted to the intensive care unit. Intensive Care Med 2015;epublished January 13th
- Abstract: Chandra. Arterial vessels behind the right internal jugular vein with relevance to central venous catheterisation. JICS 2015;epublished January 14th
- Levett. Adjunctive hyperbaric oxygen for necrotizing fasciitis. Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD007937
- Mostafaie. Beta-adrenergic blockers for perioperative cardiac risk reduction in people undergoing vascular surgery. Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD006342
- Chacko. Pressure-controlled versus volume-controlled ventilation for acute respiratory failure due to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD008807
- Brass. Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization. Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD006962
- Brass. Ultrasound guidance versus anatomical landmarks for subclavian or femoral vein catheterization. Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD011447
- Kuhn. Clinical Documentation in the 21st Century: Executive Summary of a Policy Position Paper From the American College of Physicians. Ann Intern Med 2015;epublished January 13th
- Rangasami. Tracheostomy care in 2015: Are we on the right trach? Journal of the Intensive Care Society 2015;epublished January 12th
- Chevret. Multiple imputation: a mature approach to dealing with missing data. Intensive Care Med 2015;epublished January 13th
- Mocco. Endovascular therapy for acute ischemic stroke is indicated and evidence based: a position statement. J NeuroIntervent Surg 2015;7:79-81
- Gupta. A research roadmap of future endovascular stroke trials. J NeuroIntervent Surg 2015;7:82-83
- Scott. Varieties of Standard-of-Care Treatment Randomized Trials: Ethical Implications. JAMA 2015;epublished January 15th
- Tsivgoulis. Reperfusion therapies of acute ischemic stroke: potentials and failures. Front Neurol 2014;epublished December 2nd
- Zeiler. Early Use of the NMDA Receptor Antagonist Ketamine in Refractory and Superrefractory Status Epilepticus. Critical Care Research and Practice 2015;2015:831260
- Zaky. Appraising cardiac dysfunction in liver transplantation: an ongoing challenge. Liver Int 2015;35:12–29
- Low. Hepatorenal Syndrome: Aetiology, Diagnosis, and Treatment. Gastroenterology Research and Practice 2015;2015:207012
- Dinnel. Rasburicase in the management of tumor lysis: an evidence-based review of its place in therapy. Core Evidence 2015;10:23-38
- Lancé. A general review of major global coagulation assays: thrombelastography, thrombin generation test and clot waveform analysis. Thrombosis Journal 2015;13:1
- Nomura. Clinical significance of procoagulant microparticles. Journal of Intensive Care 2015;3:2
- Ikezoe. Thrombomodulin/activated protein C system in septic disseminated intravascular coagulation. Journal of Intensive Care 2015;3:1
- Stein. What is Ebola? International Journal of Clinical Practice 2015;69:49–58
- Corey. Potential Role for Telavancin in Bacteremic Infections Due to Gram-Positive Pathogens: Focus on Staphylococcus aureus. Clin Infect Dis 2014;epublished December 3rd
- Yu. Antibacterial Mechanisms of Polymyxin and Bacterial Resistance. BioMed Research International 2015;2015:679109
- Kua. Physiologically-guided Balanced Resuscitation: An Evidence-based Approach for Acute Fluid Management in Paediatric Major Trauma. Ann Acad Med Singapore 2014;43:595-604
- Cain. Man is the new mouse: Elective surgery as a key translational model for multi-organ dysfunction and sepsis. Journal of the Intensive Care Society 2015;epublished January 7th
- Pearce. Collecting Duct Principal Cell Transport Processes and Their Regulation. CJASN 2015;10:(1)135-146
- Foley. Current knowledge and future directions of TLR and NOD signaling in sepsis. Military Medical Research
- European Space Agency astronaut Alexander Gerst created a breathtaking six minute timelapse video of earth from 12,500 high-definition photographs taken whilst aboard the International Space Station. (via Irish Times)
I hope you find these links useful.
Until next week