Welcome to the 277th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. There's loads to read this week, with numerous editorials and commentaries to make up for a relative paucity of research articles. The highlights of this week's edition are a case report demonstrating restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia; reviews on ECCO2R, acute intracerebral haemorrhage and early goal directed therapy in sepsis; as well as editorial remarks on a number of recent major trials, plus commentaries on intensive care unit benchmarking and data authorship as an incentive to data sharing. If you only have time for one paper, this this article on the management of critically ill patients with diabetes.
The 11th talk from the #CCR17 was released mid-week, with John Myburgh describing how he uses intravenous fluids. This also forms this week's Topic of the Week, starting with a paper on the case for 0.9% NaCl in tomorrow's Paper of the Day.
If you are interested in attending #CCR18, registration opens next Sunday April 9th.
- Abstract: Schell-Chaple. Effects of IV Acetaminophen on Core Body Temperature and Hemodynamic Responses in Febrile Critically Ill Adults: A Randomized Controlled Trial. Crit Care Med 2017;epublished March 17th
- Abstract: McIlroy. Effects of restricting perioperative use of intravenous chloride on kidney injury in patients undergoing cardiac surgery: the LICRA pragmatic controlled clinical trial. Intensive Care Med 2017;epublished March 25th
- Full Text: Gibbison. Corticosteroids in septic shock: a systematic review and network meta-analysis. Critical Care 2017;21:78
- Abstract: Gutiérrez-Pizarraya. Collaborative approach of individual participant data of prospective studies of de-escalation in non-immunosuppressed critically ill patients with sepsis. Expert Rev Clin Pharmacol. 2017;10(4):457-465
- Full Text: Kalil. Early Goal-Directed Therapy for Sepsis: A Novel Solution for Discordant Survival Outcomes in Clinical Trials. Crit Care Med 2017;45(4):607-614
- Abstract: Liu. The Timing of Early Antibiotics and Hospital Mortality in Sepsis. Am J Respir Crit Care Med 2017;epublished March 27th
- Abstract: Dalton. Factors Associated with Bleeding and Thrombosis in Children Receiving Extracorporeal Membrane Oxygenation (ECMO). Intensive Care Med 2017;epublished March 22nd
- Full Text: Kogelmann. Hemoadsorption by CytoSorb in septic patients: a case series. Crit Care 2017;21(1):74
- Full Text: Finkelsztein. Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit. Critical Care 2017;21:73
- Abstract: Dubé. Ultrasound evaluation of diaphragm function in mechanically ventilated patients: comparison to phrenic stimulation and prognostic implications. Thorax 2017;epublished March 30th
- Full Text: Coady. Use of the National Heart, Lung, and Blood Institute Data Repository. N Engl J Med 2017;epublished March 29th
- Full Text: Corsi. Life-threatening massive pulmonary embolism rescued by venoarterial-extracorporeal membrane oxygenation. Crit Care 2017;21(1):76
- Abstract: Habre. Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe. Lancet Respir Med 2017;epublished March 28th
- Full Text: Bassetti. Clinical characteristics and predictors of mortality in candidemia and intra-abdominal candidiasis in cirrhotic patients: a multicenter study. Intensive Care Med 2017;43:509–51
- Full Text: Saito. Efficacy of polymyxin B-immobilized fiber hemoperfusion for patients with septic shock caused by Gram-negative bacillus infection. PLoS One 2017;12(3):e0173633
- Abstract: Litton. Using Clinically Accessible Tools to Measure Sound Levels and Sleep Disruption in the ICU: A Prospective Multicenter Observational Study. Critical Care Med 2017;epublished March 30th
- Kotfis. Methods of pain assessment in adult intensive care unit patients — Polish version of the CPOT (Critical Care Pain Observation Tool) and BPS (Behavioral Pain Scale). Anaesthesiol Intensive Ther 2017;49(1):66-72
- Basu. Recent advances in Japanese encephalitis. F1000Research 2017, 6(F1000 Faculty Rev):259
- Gulati. Hemostasis in Intracranial Hemorrhage. Front Neurol 2017;;8:80
- Anathhanam. Mimics and chameleons in stroke. Clin Med 2017;17:156-160
- El Tawil. Thrombolysis and thrombectomy for acute ischaemic stroke. Clin Med 2017; 17:161-165
- Law. Management of acute intracerebral haemorrhage – an update. Clin Med 2017;17:166-172
- Morelli. Extracorporeal carbon dioxide removal (ECCO2R) in patients with acute respiratory failure. Intensive Care Med 2017;43:519–53
- Nardi. Recent Advances in Pediatric Ventilatory Assistance. F1000Research 2017;6(F1000 Faculty Rev):290
- Nadim. Intensive care unit management: Renal replacement therapy, ventilator management, volume assessment, and optimal management of hypotension. Clinical Liver Disease 2017;9:69–72
- Jalan. Novel therapies in the management of acute episodes of hepatic encephalopathy. Clinical Liver Disease 2017;9:66–68
- Zhang. Early management of sepsis with emphasis on early goal directed therapy. J Thorac Dis 2017;9(2):392-405
- Álvarez-Hernández. Rocky Mountain spotted fever in Mexico: past, present, and future. Lancet Infecrtious Dis 2017;epublished March 29th
- Bielen. Animal models of hospital-acquired pneumonia: current practices and future perspectives. Ann Transl Med 2017;5(6):132
- Beckers. Lung ischemia reperfusion injury: the therapeutic role of dipeptidyl peptidase 4 inhibition. Ann Transl Med 2017;5(6):129
- Gielis. Oxidative and nitrosative stress during pulmonary ischemia-reperfusion injury: from the lab to the OR. Ann Transl Med 2017;5(6):131
- Kucewicz-Czech. Perioperative haemodynamic optimisation in patients undergoing non-cardiac surgery — a position statement from the Cardiac and Thoracic Anaesthesia Section of the Polish Society of Anaesthesiology and Intensive Therapy. Part 1. Anaesthesiol Intensive Ther 2017;49(1):6-15
- Kucewicz-Czech. Perioperative haemodynamic optimisation in patients undergoing non-cardiac surgery — a position statement from the Cardiac and Thoracic Anaesthesia Section of the Polish Society of Anaesthesiology and Intensive Therapy. Part 2. Anaesthesiol Intensive Ther 2017;49(1):16-27
- Mukherjee. Device Thrombosis with Bioresorbable Scaffolds. N Engl J Med 2017;epublished March 29th
- Neuville. Bundle of care decreased ventilator-associated events—implications for ventilator-associated pneumonia prevention. J Thorac Dis 2017;9(3):430-433
- Murdoch. Early cerebrovascular events after transcatheter aortic valve replacement: patient- and procedure-specific predictors. J Thorac Dis 2017;9(3):434-437
- Berger. Life ain’t no SOFA—considerations after yet another failed clinical sepsis trial. J Thorac Dis 2017;9(3):438-440
- Kim. Age before duty: the effect of storage duration on mortality after red blood cell transfusion. J Thorac Dis 2017;9(3):441-443
- Du. Systemic inflammatory response syndrome, sequential organ failure assessment, and quick sequential organ failure assessment: more pieces needed in the sepsis puzzle. J Thorac Dis 2017;9(3):452-454
- Montero. We must identify patients at risk for pre-hospital sudden cardiac arrest at the early phase of myocardial infarction. J Thorac Dis 2017;9(3):466-469
- Saint. Incomplete coronary revascularization: a cautionary tale. J Thorac Dis 2017;9(3):E264-E265
- Osthoff. The EMPIRICUS trial—the final nail in the coffin of empirical antifungal therapy in the intensive care unit? J Thorac Dis 2017;9(3):E269-E273
- Koch. Do hospitals need oncological critical care units? J Thorac Dis 2017;9(3):E304-E309
- van der Voort. Quality improvement in the ICU: treat first what kills first. J Thorac Dis 2017;9(3):E310-E312
- Iqbal. Optimal medical therapy is vital for patients with coronary artery disease and acute coronary syndromes regardless of revascularization strategy. Ann Transl Med 2017;5(6):140
- Girault. Preventive post-extubation high-flow nasal oxygen therapy versus non-invasive ventilation: a substitutive or a complementary ventilatory strategy? Ann Transl Med 2017;5(6):146
- Haaksma. Ultrasound to assess diaphragmatic function in the critically ill—a critical perspective. Ann Transl Med 2017;5(5):114
- Nishimura. High-flow nasal cannula is superior to noninvasive ventilation to prevent reintubation? Ann Transl Med 2017;5(5):107
- Makdisi. Extra corporeal membrane oxygenation support: ethical dilemmas. Ann Transl Med 2017;5(5):112
- King. On vs. off pump coronary artery bypass grafting: the next chapter. Ann Transl Med 2017;5(5):116
- Rozencwajg. Meta-analysis on extracorporeal life support during cardiac arrest: do not compare apples and oranges. Ann Transl Med 2017;5(5):119
- Bonaventura. Coronary stenting: A matter of revascularization. World J Cardiol 2017;9(3):207-211
- Salluh. Understanding intensive care unit benchmarking. Intensive Care Med 2017;epublished March 15th
- Genga. How much excess fluid impairs outcome of sepsis? Intensive Care Med 2017;epublished March 27th
- Bein. Understanding ethical decisions for patients on extracorporeal life support. Intensive Care Med 2017;epublished March 27th
- Bein. Empathy: some thoughtful reflections among a favorable attitude. Intensive Care Med 2017;epublished March 28th
- Cutuli. ‘σήψις’ yesterday, sepsis nowadays: what’s changing? J Thorac Dis 2017;9(2):E166-E167
- Bos. A new prediction score for critically ill patients—do we need an Apgar score for acute respiratory distress syndrome? J Thorac Dis 2017;9(2):E142-E145
- Garraud. Effect of “old” versus “fresh” transfused red blood cells on patients’ outcome: probably more complex than appears. J Thorac Dis 2017;9(2):E146-E148
- Makdisi. Use of distal perfusion in peripheral extracorporeal membrane oxygenation. Ann Transl Med 2017;5(5):103
- Bierer. Data Authorship as an Incentive to Data Sharing. N Engl J Med 2017;epublished March 29th
- Katz. Scientific Drought, Golden Eggs, and Global Leadership — Why Trump’s NIH Funding Cuts Would Be a Disaster. N Engl J Med 2017;epublished March 29th
- Mello. Medical Liability — Prospects for Federal Reform. N Engl J Med 2017;epublished March 29th
- Carpenter. Scott Gottlieb and the Credibility of U.S. Therapeutics. N Engl J Med 2017;epublished March 29th
- Chandra. An FDA Commissioner for the 21st Century. N Engl J Med 2017;epublished March 29th
- Jost. Trump’s Executive Order on Health Care — Can It Undermine the ACA if Congress Fails to Act? N Engl J Med 2017;376:1201-1203
- Guervilly. Respiratory rate and peak inspiratory pressure, new targets from the LUNG SAFE study analysis or physiopathological artifacts? J Thorac Dis 2017;9(2):225-227
- Maitra. Checklist & prompting in intensive care unit: quality of care is improved but long way to go for better outcome. J Thorac Dis 2017;9(2):228-229
There are just 5 months left unit Das SMACC and all tickets have now been sold for the main conference. If you are interested in attending the workshops, there are a very small number of tickets left for the Hardcore Intensive Care workshop being organised by Steve Mathieu and Sarah Yong. With a superb international faculty, this half-day event will address your burning critical care questions.
(Image from Chensiyuan via Wikipedia)
The Critical Care Symposium (CCS) was initiated to satisfy the purpose of creating a world-class environment for medical enrichment in the North of England, particularly in Manchester. It was envisioned as a common informal platform wherein professionals from the field of critical care could provide and enhance the knowledge of delegates on current practices and related fields of interest.
Now in its 14th year, the annual conference regularly has renowned speakers from around the world and attracts more than 400 delegates. And this year is no different. In recent years a parallel course on ultrasound has been conducted alongside the conference that provides ample hand-on experience over two days. This year will host the 7th Ultrasound in Acute Care. For more information please visit http://critcaresymposium.co.uk.
The ANZICS/ACCCN Annual Scientific Meeting, which incorporates the annual Paediatric and Neonatal Intensive Care Conference, will be held at the Gold Coast Convention and Exhibition Centre, 11-13 October 2017. The Annual Scientific Meeting will be the preeminent critical care conference in Australasia for the calendar year and will be an important platform that will allow doctors, nurses and allied health practitioners to meaningfully connect and discuss new developments and research in the field of intensive and critical care.
The theme of the Meeting is “Thinking Outside the Flags” and will focus upon innovative and challenging advances that lie outside the safe zone of current practice, as well as the potential dangers that they may bring. A number of highly regarded international speakers will join our distinguished national and local speakers, experts in the field of intensive care medicine, nursing and allied health, promising delegates an exciting and challenging program.
Registration and the call for abstracts will open on 20 March 2017. For further information or to express your interest in attending, please visit http://intensivecareasm2017.com.au/.
Critical Care Horizons is a fresh new voice in the critical care literature, offering thought-provoking, cutting-edge commentary and opinion papers, plus state-of-the-art review articles. The journal is free to publish with and free to read, opening authorship opportunity to all. The energetic editorial board consists of a deliberate mix of clinicians active in social media and world renowned academics, all driven by a desire to improve the care we offer our patients, and operate without financial gain or incentive. If you have an idea for a paper, and can say it in an engaging manner, please get in touch. We also need peer reviewers.
COI - I am the editor-in-chief of this new journal, but work in a voluntary capacity, as do all the editors.
I hope you find these links useful.
Until next week